Results 231 to 240 of about 3,098,024 (301)

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Computer-Aided Drug Design Across Breast Cancer Subtypes: Methods, Applications and Translational Outlook. [PDF]

Int J Mol Sci
Tian W, Hu Y, Gao X, Yang J, Jiang W.
europepmc   +1 more source

Biopolymer Hydrogel-Based Nanocomposites Functionalized with Natural Products for Wound Dressings: Translational Advances in Drug Design, Development, and Therapeutic Wound Care. [PDF]

Drug Des Devel Ther
Ranatunga B, Sekar M, Hashmi AR, Zahra F, Ravi RN, Prashantha Kumar BR, Al Hamod M, Al Hamood N, Begum MY, Wong LS, Kumarasamy V, Molugulu N.   +11 more
europepmc   +1 more source

Manifold-constrained nucleus-level denoising diffusion model for structure-based drug design. [PDF]

Proc Natl Acad Sci U S A
Liu S, Yan L, Du W, Liu W, Li Z, Guo H, Borgs C, Chayes J, Anandkumar A.   +8 more
europepmc   +1 more source

Vanillin Derivatives in Drug Design: Structure-Activity Relationship (SAR) Hotspots and Synthetic Pathways for Enhanced Pharmacological Activity. [PDF]

ACS Omega
Suleiman M, Sankaranarayanan M, Theva Das K, Amran SI, Berezin V, Andrey B, Jamalis J.   +6 more
europepmc   +1 more source

Qsarna: An Online Tool for Smart Chemical Space Navigation in Drug Design. [PDF]

J Chem Inf Model
Cieślak M, Łęski J, Krzysztyńska-Kuleta O, Kalinowska-Tłuścik J, Danel T.   +4 more
europepmc   +1 more source

Advancing in silico drug design with Bayesian refinement of AlphaFold models

Sen S, Hoff SE, Morozova TI, Schnapka V, Bonomi M.   +4 more
europepmc   +1 more source

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New Designer Drugs

Emergency Medicine Clinics of North America, 2021
In recent years, there has been an emergence of numerous novel drugs. Such toxicity may occur in both adolescents and adults. This article discusses the opioid epidemic and several emerging opioids, including buprenorphine, loperamide, fentanyl, fentanyl derivatives, and others.
Michael, Levine, Frank, Lovecchio
openaire   +2 more sources

Rational drug design

European Journal of Pharmacology, 2009
In this article, current knowledge of drug design is reviewed and an approach of rational drug design is presented. The process of drug development is challenging, expensive, and time consuming, although this process has been accelerated due to the development of computational tools and methodologies.
Soma, Mandal, Mee'nal, Moudgil, Sanat K, Mandal   +2 more
openaire   +2 more sources