Results 71 to 80 of about 3,098,024 (301)

Outcomes of Live Virus Vaccination in Patients With Vascular Anomalies Being Treated With Sirolimus

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Live vaccination in patients with vascular anomalies (VA) receiving sirolimus remains controversial due to immunosuppressive effects and theoretical risks. Procedure This single‐center retrospective study included patients with VA less than 4 years old at the start of sirolimus therapy who were incompletely vaccinated.
Svatava Merkle, Kiersten Ricci, Kelly Blache, Rebecca A. Marsh, Adrienne M. Hammill, Elissa Engel   +5 more
wiley   +1 more source

Thermochemical, spectral and biological activity prediction of some methylpyridine derivatives: a computational approach

Discover Chemistry
Pyridine and its derivatives play a vital role in pharmaceutical and pesticide applications. However, prolonged exposure to pyridine can lead to significant health risks due to its ability to enter the body via inhalation and absorption.
Md. Arifur Rahman, S. M. Mehedi Afnan Rejve, Md. Ruhul Amin Niloy, Mim Afsari, Umma Hany Sawon, Fahima Akter, Rafi Ahmed Miah, Md. Byzed Hasan, Monir Uzzaman   +8 more
doaj   +1 more source

Nothing Besides Remains: Preserving the Scientific and Cultural Value of Paleontological Resources in the United States [PDF]

, 2005
Receptor occupancy assessed by Positron Emission Tomography (PET) can provide important translational information to help bridge information from one drug to another or from animal to man.
Chew, Alexa Z.
core   +1 more source

The Fate (Outcome) of Clinically Apparent Single Lesion and Oligofocal Nephroblastomatosis Treated According to SIOP/GPOH Protocols for Wilms Tumor

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The management of clinically apparent single lesions or oligofocal nephroblastomatosis, a facultative precursor of nephroblastoma, remains debated. Methods We retrospectively analyzed 37 patients with clinically apparent single or oligofocal nephroblastomatosis (two to three lesions per kidney) among 2347 patients registered between
Nils Welter, Jens‐Peter Schenk, Jenny Wegert, Manfred Gessler, Leo Kager, Stefan Wagenpfeil, Marina Müller, Jean‐Michel Wolff, Joerg Fuchs, Steven W. Warmann, Clemens‐Magnus Meier, Jochen Hubertus, Christian Rübe, Christian Vokuhl, Patrick Melchior, Lena Tschirner, Norbert Graf, Rhoikos Furtwängler   +17 more
wiley   +1 more source

Removal of Tetracycline in Sewage and Dairy Products with High-Stable MOF

Molecules, 2020
Serious environmental and human health problems caused by the abuse of antibiotics have attracted worldwide concern. Recently, metal−organic frameworks (MOFs) with high porosity have drawn wide attention for their effects in the adsorption and ...
Kan Li, Jing-jing Li, Ni Zhao, Ying Ma, Bin Di   +4 more
doaj   +1 more source

Molecular Dynamics Studies on HIV-1 Protease: Drug Resistance and Folding Pathways [PDF]

, 2001
Drug resistance to HIV-1 Protease involves accumulation of multiple mutations in the protein. Here we investigate the role of these mutations by using molecular dynamics simulations which exploit the influence of the native-state topology in the folding ...
Carloni, Paolo, Cecconi, Fabio, Maritan, Amos, Micheletti, Cristian   +3 more
core   +2 more sources

Graphene Oxide Foam Supported Titanium(IV): Recoverable Heterogeneous Catalyst for Efficient, Selective Oxidation of Arylalkyl Sulfides to Sulfoxides Under Mild Conditions

Scientific Reports, 2017
An efficient and environmentally friendly method was designed for the oxidation of sulfides to sulfoxides with a recyclable, carbon-skeleton-based heterogeneous catalyst developed by titanium sulfate [Ti(SO4)2] mineralization on the surface of graphene ...
Qinghe Wang, Wenxi Ma, Qiaolin Tong, Guijie Du, Jian Wang, Meng Zhang, Hailun Jiang, Huali Yang, Yongxiang Liu, Maosheng Cheng   +9 more
doaj   +1 more source

A pair of new enantiomers of xanthones from the stems and leaves of Cratoxylum cochinchinense

Chinese Medicine, 2019
Background The simple and caged xanthones from Clusiaceae showed significant antineoplastic activity. This study aims to identify structural diverse xanthones and search for novel antitumor natural products from this family plants. Methods The structures
Cuicui Jia, Chi Gong, Hong Chen, Jing Pu, Dahong Li, Zhanlin Li, Huiming Hua   +6 more
doaj   +1 more source

Mapping the druggable allosteric space of G-protein coupled receptors: a fragment-based molecular dynamics approach. [PDF]

, 2010
To address the problem of specificity in G-protein coupled receptor (GPCR) drug discovery, there has been tremendous recent interest in allosteric drugs that bind at sites topographically distinct from the orthosteric site. Unfortunately, structure-based
Ivetac, Anthony, McCammon, J Andrew
core   +2 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source