Results 31 to 40 of about 2,491,987 (318)

Correction to: Radiological evaluation of malignant pleural mesothelioma - defining distant metastatic disease

open access: yesBMC Cancer, 2021
An amendment to this paper has been published and can be accessed via the original article.
Dearbhaile Catherine Collins   +11 more
doaj   +1 more source

Self-Nano-Emulsifying Drug-Delivery Systems: From the Development to the Current Applications and Challenges in Oral Drug Delivery.

open access: yes, 2020
Approximately one third of newly discovered drug molecules show insufficient water solubility and therefore low oral bio-availability. Self-nano-emulsifying drug-delivery systems (SNEDDSs) are one of the emerging strategies developed to tackle the issues
Beloqui Garcia, Ana   +7 more
core   +1 more source

Melatonergic drugs in development

open access: yesClinical Pharmacology: Advances and Applications, 2014
Melatonin (N-acetyl-5-methoxytryptamine) is widely known as "the darkness hormone". It is a major chronobiological regulator involved in circadian phasing and sleep-wake cycle in humans. Numerous other functions, including cyto/neuroprotection, immune modulation, and energy metabolism have been ascribed to melatonin.
CAROCCI, ALESSIA   +2 more
openaire   +6 more sources

Dopaminergic cell protection and alleviation of neuropsychiatric disease symptoms by VMAT2 expression through the class I HDAC inhibitor TC‐H 106

open access: yesPharmacology Research & Perspectives, 2023
The importance of vesicular monoamine transporter 2 (VMAT2) in dopamine regulation, which is considered crucial for neuropsychiatric disorders, is currently being studied.
Heejin Lee   +14 more
doaj   +1 more source

Drug Development☆

open access: yes, 2007
openAccessArticle: False ; cover date: 2015-01-01 ; pii: B978-0-12-801238-3.04980-1 ; Harvest Date: 2016-01-06 13:08:13 ; issueName: ; Page Range: - ; href scidir: http://www.sciencedirect.com/science/article/pii/B9780128012383049801 ; pubType:
L., Wecker, Wecker, L., Krzanowski, J.
openaire   +3 more sources

Country Program Evaluation: Costa Rica (2006-2010) [PDF]

open access: yes, 2010
The Bank\u27s country strategy with Costa Rica 2006-2010 correctly identified the country\u27s main development challenges in 2006 (the baseline used by the Bank to prepare the strategy): the difficulty of forging linkages between the most dynamic ...
Inter-American Development Bank
core   +1 more source

Preface for buccal drug delivery theme issue [PDF]

open access: yes, 2014
During the past years, buccal drug delivery has attracted the attention of researchers looking for alternative delivery routes of administration. As an alternative to oral drug delivery, the buccal mucosal route avoids the passage through the acidic ...
Morales, Javier Octavio   +3 more
core   +1 more source

Using Ex Vivo Porcine Jejunum to Identify Membrane Transporter Substrates: A Screening Tool for Early—Stage Drug Development

open access: yes, 2020
Robust, predictive ex vivo/in vitro models to study intestinal drug absorption by passive and active transport mechanisms are scarce. Membrane transporters can significantly impact drug uptake and transporter-mediated drug–drug interactions can ...
Yvonne E. Arnold, Yogeshvar N. Kalia
core   +1 more source

Breve 11: Value Based Drug Reimbursement: Introduction to the Main Features of the German Pharmaceutical Policy

open access: yes, 2016
This Breve is based on a webinar presented by Dr. Wolfgang Greiner, professor at the University of Bielefeld, member of the scientific Advisorygroup of the German Institute for Quality and Efficiency in Health Care (IQWiG)and the EuroQol group.
Inter-American Development Bank
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

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