Results 21 to 30 of about 2,491,987 (318)
Scientific Reports, 2021 Long-term stability of monoclonal antibodies to be used as biologics is a key aspect in their development. Therefore, its possible early prediction from accelerated stability studies is of major interest, despite currently being regarded as not ...
Drago Kuzman +5 more
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Dual-drug amorphous formulation of gliclazide
, 2021 Amorphization is a well-established strategy to enhance the dissolution properties of poorly water-soluble drugs. However, the amorphous state is inherently unstable toward recrystallization.
Aljohani, Marwah +2 more
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mAbs, 2023 Excipients are added to biopharmaceutical formulations to enhance protein stability and enable the development of robust formulations with acceptable physicochemical properties, but the mechanism by which they confer stability is not fully understood ...
Chunting Zhang +11 more
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Drug Policies and Development [PDF]
, 2020 The 12th volume of International Development Policy explores the relationship between international drug policy and development goals, both current and within a historical per-spective.
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Immuno-oncology combinations: raising the tail of the survival curve
Cancer Biology & Medicine, 2016 There have been exponential gains in immuno-oncology in recent times through the development of immune checkpoint inhibitors. Already approved by the U.S.
Samuel J. Harris +3 more
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Drug Development: Stages of Drug Development [PDF]
Journal of Pharmacovigilance, 2015 New drug development program for the different compound is initiated because there is a disease or clinical condition without suitable pharmacotherapeutic products available. New drug development can proceed along varied pathways for different compounds.
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Drug development, radiolabeled drugs and PET
Annals of Medicine, 1999 Positron emission tomography (PET) provides noninvasive in vivo quantitative pharmacokinetic and pharmacodynamic information on novel and established drugs. Because only very low amounts of the (potential) drug have to be administered, far below toxicity levels, human studies can be carried out even before the drug is entered in phase I studies.
Vaalburg, W +2 more
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Plant Secondary Metabolites Used for the Treatment of Diseases and Drug Development
, 2022 The importance of natural products in medicine, and in particular, plant secondary metabolites used for the treatment of diseases and drug development, has been obvious for several thousands of years [...
Pavel B. Drašar
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Cytomics and drug development [PDF]
Cytometry Part A, 2007 Drug discovery is fundamentally focused on increasing the number and novelty of medicines, while containing the associated costs. High costs impact on healthcare delivery and the range of diseases for which medicines become available. Pace has been increased via combinatorial chemistry, genomics knowledge, proteomics technologies, new target validation
Paul J, Smith, I A, Khan, R J, Errington
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Journal of Ovarian Research, 2022 Background The Ayurvedic system of medicine mentions the use of seeds of Bryonopsis laciniosa (L.) Naud. (also known as Shivlingi due to their unique structure resembling a ‘Shivling’) for treating sexual dysfunction, impaired fertility, and as a general
Acharya Balkrishna +4 more
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