Results 251 to 260 of about 5,785,146 (400)

The value of plants used in traditional medicine for drug discovery.

, 2001
Daniel S. Fabricant, N.R. Farnsworth
openalex   +1 more source

The Integration of High Throughput Technologies for Drug Discovery [PDF]

, 2001
Gregory P. Sabbatini, William A. Shirley, David L. Coffen   +2 more
openalex   +1 more source

An approach for coherent periodogram averaging of tilt‐series data for improved contrast transfer function estimation

FEBS Open Bio, EarlyView.
The contrast transfer function (CTF) is an imaging aberration that is a major resolution‐limiting factor in cryo‐electron microscopy (cryo‐EM). Precise CTF estimation is key to overcoming this limitation, but is particularly challenging in cryo‐electron tomography (cryo‐ET) data. Here, we present an approach for using geometric information to assist in
Sagar Khavnekar, William Wan
wiley   +1 more source

Drug Discovery and Development

JACS Au
Carole Duboc, Sabine L. Flitsch
openaire   +3 more sources

Editorial: Drug discovery from herbal medicines/polypeptides for neurological diseases. [PDF]

Front Pharmacol
Liang Q, Zhang J, Lin L, Wang J.
europepmc   +1 more source

The role of circular RNAs in regulating cytokine signaling in cancer

FEBS Open Bio, EarlyView.
Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi, Swati, Amit Mishra, Amaresh Panda, Vivek Sharma   +4 more
wiley   +1 more source

Exploring Macrocyclic Chemical Space: Strategies and Technologies for Drug Discovery. [PDF]

Pharmaceuticals (Basel)
Kim T, Baek E, Kim J.
europepmc   +1 more source

Functional Genomics and Cardiovascular Drug Discovery

, 2001
Richard Lee
openalex   +1 more source

The integration of functional genomics, combinatorial chemistry and nanotechnology into a miniaturized drug discovery process [PDF]

, 2001
Manfred Auer
openalex   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source