Results 271 to 280 of about 5,785,146 (400)

HTPS Flow Cytometry: A Novel Platform for Automated High Throughput Drug Discovery and Characterization

, 2001
Bruce S. Edwards, Frederick W. Kuckuck, Eric R. Prossnitz, John Ransom, Larry A. Sklar   +4 more
openalex   +1 more source

The edge visualization metric: Quantifying the improvement of lung SBRT target definition with 4D CBCT

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Four‐dimensional cone‐beam CT (4D CBCT) incorporates oversampling of 3D data to reconstruct multi‐phase CBCT data sets representing distinct phases of the breathing cycle based on a diaphragmatic correlate of respiratory motion. Motion artifacts and blurring can be reduced relative to three‐dimensional cone‐beam (3D CBCT), allowing ...
Colton Baley, Sam Andersen, Clark Anderson, Shraddha Dalwadi, Daniel L. Saenz   +4 more
wiley   +1 more source

AI In Action: Redefining Drug Discovery and Development. [PDF]

Clin Transl Sci
Kanakia A, Sale M, Zhao L, Zhou Z.
europepmc   +1 more source

Drug Metabolism Studies in Discovery Stage using human materials

, 2001
Yoshinobu Yoshimura
openalex   +2 more sources

Producing high quality cranial SRS plans with 4Pi planning technique in a commercial clinical solution

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To generate high‐quality stereotactic radiosurgery (SRS) plans for single cranial lesions using 4Pi planning technique and compare these to our clinical “status quo” plans. Methods Eighteen vestibular schwannoma (VS) patients previously planned with Varian Eclipse RapidArc and treated on a Varian TrueBeam using 6FFF MV photon beams ...
Ganesh Narayanasamy, Nishan Shrestha, Milan Bimali, Fen Xia, Zhong Su   +4 more
wiley   +1 more source

Enhanced analysis of gating latency in 0.35T MR‐linac through innovative time synchronization of a motion phantom and plastic scintillation detector

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose This study aims to evaluate how different gantry angles, breathing rates (BPM), cine image speeds, and tracking algorithms affect beam on/off latency and the subsequent impact on target dose for a 0.35T MR‐Linac with a 6 MV FFF beam.
Mateb Al Khalifa, Tianjun Ma, Haya Aljuaid, Siyong Kim, William Y. Song   +4 more
wiley   +1 more source

Bayesian Inference for Drug Discovery by High Negative Samples and Oversampling. [PDF]

Bioinform Biol Insights
Le MH, Dao NA, Dang XT.
europepmc   +1 more source

High-Density Miniaturized Thermal Shift Assays as a General Strategy for Drug Discovery

, 2001
Michael W. Pantoliano, Eugene C. Petrella, Joseph D. Kwasnoski, Victor S. Lobanov, James C. Myslik, E. R. Graf, Ted Carver, Eric D. Asel, Barry A. Springer, Pamela Lane, F.R. Salemme   +10 more
openalex   +1 more source

Demonstration of an enhanced dosing pattern for debulking large and bulky unresectable tumors via differential hole‐size spatially fractionated radiotherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose/objective We propose a novel lattice deployment for spatially fractionated radiotherapy (SFRT) treatments. In this approach, a larger diameter high‐dose sphere is centrally placed in the bulky tumor mass and surrounded by smaller diameter high‐dose spheres.
Joshua Misa, William St. Clair, Damodar Pokhrel   +2 more
wiley   +1 more source

Drug discovery in reverse [PDF]

Nature, 2004
openaire   +3 more sources