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Use of P450 Enzymes for Late-Stage Functionalization in Drug Discovery. [PDF]
J Med ChemPoon V +19 more
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Molecular Hybridization of Naphthoquinones and Thiazoles: A Promising Strategy for Anticancer Drug Discovery. [PDF]
Pharmaceuticals (Basel)de Moraes LGC, Santos TB, da Rocha DR.
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Drug News & Perspectives, 2005
New brief reports this month describe five timely topics: IDO inhibitors have demonstrated antitumor properties by increasing immune response to tumors and improving chemotherapy effectiveness. One of the current therapeutic efforts for Alzheimer's disease is directed towards blocking the gamma-secretase activity, thus reducing amyloid-beta production.
V, Khurdayan, M, Cullell-Young
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New brief reports this month describe five timely topics: IDO inhibitors have demonstrated antitumor properties by increasing immune response to tumors and improving chemotherapy effectiveness. One of the current therapeutic efforts for Alzheimer's disease is directed towards blocking the gamma-secretase activity, thus reducing amyloid-beta production.
V, Khurdayan, M, Cullell-Young
openaire +2 more sources
Current Topics in Medicinal Chemistry, 2003
In recent years, tools for the development of new drugs have been dramatically improved. These include genomic and proteomic research, numerous biophysical methods, combinatorial chemistry and screening technologies. In addition, early ADMET studies are employed in order to significantly reduce the failure rate in the development of drug candidates. As
Oliver, Schwardt +2 more
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In recent years, tools for the development of new drugs have been dramatically improved. These include genomic and proteomic research, numerous biophysical methods, combinatorial chemistry and screening technologies. In addition, early ADMET studies are employed in order to significantly reduce the failure rate in the development of drug candidates. As
Oliver, Schwardt +2 more
openaire +2 more sources
Expert Opinion on Drug Discovery, 2007
Ayurveda is a major traditional system of Indian medicine that is still being successfully used in many countries. Recapitulation and adaptation of the older science to modern drug discovery processes can bring renewed interest to the pharmaceutical world and offer unique therapeutic solutions for a wide range of human disorders. Eventhough time-tested
Premalatha, Balachandran +1 more
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Ayurveda is a major traditional system of Indian medicine that is still being successfully used in many countries. Recapitulation and adaptation of the older science to modern drug discovery processes can bring renewed interest to the pharmaceutical world and offer unique therapeutic solutions for a wide range of human disorders. Eventhough time-tested
Premalatha, Balachandran +1 more
openaire +2 more sources
1988
The role of the pharmaceutical industry has been defined as the application of “basic knowledge in biology and chemistry to the discovery of new medicines” [1]. While it is generally acknowledged that the industry has made significant contributions to the health and financial well-being of society in this role [2], there is, by and large, no single ...
M, Williams, G L, Neil
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The role of the pharmaceutical industry has been defined as the application of “basic knowledge in biology and chemistry to the discovery of new medicines” [1]. While it is generally acknowledged that the industry has made significant contributions to the health and financial well-being of society in this role [2], there is, by and large, no single ...
M, Williams, G L, Neil
openaire +2 more sources