Results 41 to 50 of about 21,869 (255)

Understanding factors that contribute to the disposal of unused opioid medication

Journal of Pain Research, 2019
Daniel E Buffington,1,2 Alyson Lozicki,2 Thomas Alfieri,3 T Christopher Bond3 1University of South Florida, College of Medicine, 2University of South Florida, College of Pharmacy, Tampa, FL 33617, USA; 3Purdue Pharma LP, Medical Affairs, Stamford, CT ...
Buffington DE, Lozicki A, Alfieri T, Bond TC   +3 more
doaj  

Insights from a National Survey on Controlled Substance Diversion Practices in U.S. Hospital Pharmacies: Opportunities for Enhanced Surveillance and Compliance

Pharmacy
This study explored controlled substance (CS) diversion surveillance practices within hospital pharmacies across the United States. A survey with questions based on published CS diversion risk points was conducted in May 2024.
Samantha S. Bastow, Eric P. Borrelli, Julia D. Lucaci, Heather Nelkin, April Graves, Amanda Hays   +5 more
doaj   +1 more source

Population diversity in oncology drug responses and implications to drug development

Chinese Clinical Oncology, 2019
Cancer drug development is proceeding at a rapid pace, with drug approvals in oncology outpacing the other disease indications. With high population growth and economic development of Asian countries, access to cancer drugs becomes a paramount necessity.
Robert, Walsh, Boon-Cher, Goh
openaire   +2 more sources

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, EarlyView.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Microengineered Gradient Hydrogels for Mechanobiology

Advanced Healthcare Materials, EarlyView.
Gradient hydrogels are used to mimic the mechanical heterogeneity in native tissues, offering powerful in vitro platforms to study cell‐material interactions in diverse pathophysiological contexts. Here, we present a comprehensive review of the design and experimental considerations for stiffness gradient hydrogels, discussing exemplary achievements ...
Shin Wei Chong, Deepu Ashok, Anna Waterhouse, Marcela M. M. Bilek, Daniele Vigolo   +4 more
wiley   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Understanding the social networks that contribute to diversion in hospital inpatient pharmacies: A social network analysis

Exploratory Research in Clinical and Social Pharmacy
Background: Controlled substances (CS) are ‘diverted’ (stolen) from healthcare facilities via many integrated and diverse mechanisms due to a lack of safeguards.
Troy Francis, Maaike de Vries, Mark Fan, Sonia Pinkney, Reza Yousefi-Nooraie, Mathieu Ouimet, Valeria E. Rac, Patricia Trbovich   +7 more
doaj   +1 more source

Tracking Spatiotemporal Extracellular Matrix Evolution and Tissue Fusion in 3D Microtissues via Click Chemistry‐Based Metabolic Labelling

Advanced Healthcare Materials, EarlyView.
Metabolic labeling of nascent proteins in 3D microtissue spheroids provides a powerful analytical approach for large‐scale tissue engineering. Incorporation of non‐canonical amino acids with fluorescent tagging enables spatiotemporal investigation of extracellular matrix deposition and its evolution during multicellular tissue development and fusion ...
Theresa Koenig, F. Max Yavitt, Laura Veenendaal, Tim B. F. Woodfield   +3 more
wiley   +1 more source

Advances in the delivery of buprenorphine for opioid dependence

Drug Design, Development and Therapy, 2017
Richard N Rosenthal,1 Viral V Goradia2 1Department of Psychiatry, Addiction Institute at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, 2Department of Psychiatry, Upstate Medical University, Syracuse, NY, USA Abstract: Opioid use ...
Rosenthal RN, Goradia VV
doaj  

Doctor Shopping Behavior and the Diversion of Prescription Opioids

Substance Abuse: Research and Treatment, 2017
Objectives: “Doctor shopping” as a means of prescription opioid diversion is examined. The number and percentage of prescriptions and morphine-equivalent milligrams diverted in this manner are estimated by state and molecule for the period 2008-2012 ...
Ronald Simeone
doaj   +1 more source