Results 241 to 250 of about 192,321 (311)

Vitreous Substitutes in Vitreoretinal Surgery: From Native Vitreous Physiology to Bioengineered Experimental Replacements. [PDF]

J Funct Biomater
Avitabile A, Cannizzaro L, Rusciano D.
europepmc   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

FourierDrug: a domain generalization framework for robust drug response prediction via frequency-space asymmetric attention. [PDF]

Bioinformatics
Song R, Bai Y, Liu X, Liu H.
europepmc   +1 more source

Preclinical evaluation of AHR-1118, a potential antidepressant drug.

Current therapeutic research, clinical and experimental, 1970
D N, Johnson, W H, Funderburk, J W, Ward
openaire   +1 more source

Emerging agents that target signaling pathways in cancer fibroblast cells (Review). [PDF]

Int J Oncol
Wan Y, Liu XQ, Liu D, Li KD, Zhang DD.
europepmc   +1 more source

Deep Unsupervised Domain Adaptation for Translating Cancer Dependency Maps From Cell Lines to Breast Cancer Tumor Genomics. [PDF]

Genet Epidemiol
Shi Y, Xu W, Hu P.
europepmc   +1 more source

Can Scorpion Venom Peptides Be Safely Used in Cardiovascular Therapy: A Systematic Review. [PDF]

Cureus
Binorkar SV, Sawant R, Ukey RN, Bhat R.
europepmc   +1 more source

Preclinical screening models in anticancer drug development: strengths, limitations, and translational challenges. [PDF]

Front Pharmacol
Yadav R, Singh S, Kumar S, Kolay A, Sharma H, Dorai R, Sharma AK, Singh RP, Yadav MK.   +8 more
europepmc   +1 more source