Results 231 to 240 of about 18,950,887 (401)

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

Molecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci, Izzet Akiva, Yavuz Hakan Ozon, Hakan Berkil, Huseyin Karadayi, Omer Dizdar, Suayib Yalcin   +6 more
wiley   +1 more source

A SCORING SYSTEM FOR ABSTINENCE SYNDROME IN MORPHINE DEPENDENT MICE AND APPLICATION TO EVALUATE MORPHINE TYPE DEPENDENCE LIABILITY OF DRUGS

, 1973
Hiroshi Kaneto, Masao Koida, H Nakanishi, Hiroshi Sasano   +3 more
openalex   +1 more source

Specific determination of hepatitis B e antigen by antibodies targeting precore unique epitope facilitates clinical diagnosis and drug evaluation against hepatitis B virus infection. [PDF]

Emerg Microbes Infect, 2021
Wang SJ, Chen ZM, Wei M, Liu JQ, Li ZL, Shi TS, Nian S, Fu R, Wu YT, Zhang YL, Wang YB, Zhang TY, Zhang J, Xiong JH, Tong SP, Ge SX, Yuan Q, Xia NS.   +17 more
europepmc   +1 more source

Evaluation of antianginal drugs. [PDF]

Circulation, 1982
openaire   +3 more sources

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

Studies on Methods for Evaluation of Anticoccidial Drugs in Vitro

, 1974
Keizaburo ITAGAKI, Misao Tsubokura, Koichi Otsuki   +2 more
openalex   +2 more sources

Generation of human vascularized and chambered cardiac organoids for cardiac disease modelling and drug evaluation. [PDF]

Cell Prolif
Yang J, Lei W, Xiao Y, Tan S, Yang J, Lin Y, Yang Z, Zhao D, Zhang C, Shen Z, Hu S.   +10 more
europepmc   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Studies on the evaluation of crude drug. I. Quantitative estimation of anthraquinones in Cassia seeds.

, 1978
Masaji Koshioka, Yoshio Takino
openalex   +2 more sources

Evaluation of drug-antibody conjugates in the treatment of human myelosarcomas transplanted in nude mice [PDF]

, 1980
Zulkiflee Abd Latif, B B Lozzio, Carl J. Wust, S Krauß, Mario Carlos Aggio, Carmen B. Lozzio   +5 more
openalex   +1 more source