Results 251 to 260 of about 1,388,675 (309)
FEBS Open Bio, EarlyView.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
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Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
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EVALUATION OF ANTIEPILEPTIC DRUGS
Archives of Neurology And Psychiatry, 1950TWO PRINCIPAL electric shock methods have been employed for the laboratory appraisal of anticonvulsant drugs: ( a ) the method of Putnam and Merritt 1 and ( b ) that of Toman, Swinyard and Goodman. 2 In the former, the anticonvulsant potency of a compound is determined by its ability to raise the electric shock convulsion threshold in the cat ...
G, CHEN, C R, ENSOR
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The evaluation of cytotoxic drugs
Cancer Treatment Reviews, 1979info:eu-repo/semantics ...
Von Hoff, Daniel D.D. +2 more
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The evaluation of antirheumatic drugs
Current Medical Research and Opinion, 1973SummaryThe available methods of evaluation of an antirheumatic compound in a clinical trial situation are discussed. The techniques of single-blind and double-blind studies are described and their respective merits analysed. Proposed new techniques for the measurement of joint inflammation are reviewed.
P, Lee +3 more
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American Journal of Health-System Pharmacy, 1986
Drug reviews appearing in Clinical Pharmacy, Drug Intelligence and Clinical Pharmacy (DICP), Drugs, and Pharmacotherapy from January 1982 through December 1984 were evaluated for number, duplication among journals, timeliness, scope, and format. The design of this study was primarily quantitative rather than qualitative.
N M, Hendrickson, A B, Amerson
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Drug reviews appearing in Clinical Pharmacy, Drug Intelligence and Clinical Pharmacy (DICP), Drugs, and Pharmacotherapy from January 1982 through December 1984 were evaluated for number, duplication among journals, timeliness, scope, and format. The design of this study was primarily quantitative rather than qualitative.
N M, Hendrickson, A B, Amerson
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Evaluation of the teratogenicity of drugs
Clinical Pharmacology & Therapeutics, 1964The detection of the teratogenic effect of drugs remains a challenge. The sudden appearance of the problem has baffled pharmacologists. The testing of the teratogenic action of a new drttg requires a systematic and complete investigation, without bias, based on the chemical s1rttctttre or pharmacologic action.
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Evaluation of drug–drug interactions with fesoterodine
European Journal of Clinical Pharmacology, 2009To assess drug-drug interactions of fesoterodine with cytochrome P450 (CYP) 3A4 inhibitor (ketoconazole), inducer (rifampicin), and substrates (ethinylestradiol and levonorgestrel).Effects of ketoconazole 200 mg twice daily and rifampicin 600 mg twice daily on fesoterodine 8 mg once daily were investigated in CYP2D6 extensive metabolizers (EMs) and ...
Bimal, Malhotra +2 more
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