Results 241 to 250 of about 18,950,887 (401)

Human Motor System-Based Biohybrid Robot-On-a-Chip for Drug Evaluation of Neurodegenerative Disease. [PDF]

Adv Sci (Weinh)
Shin M, Ha T, Lim J, An J, Beak G, Choi JH, Melvin AA, Yoon J, Choi JW.   +8 more
europepmc   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Drug treatment programs in Pennsylvania. A statewide evaluation.

, 1975
John C. Ball, Harold Graff
openalex   +1 more source

Construction and Drug Evaluation Based on Convolutional Neural Network System Optimized by Grey Correlation Analysis.

Comput Intell Neurosci, 2021
Teng H.
europepmc   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

Fundamental Studies on the Evaluation of the Crude Drugs. IV. Quantitative Analysis of Constituents in the Crude Drugs by Rod-Thin-Layer Chromatography with FID. (1). Determination of Glycyrrhizin in Liquorice Roots

, 1975
Tsuneo Namba, Masao Yoshizaki, Tsuyoshi Tomimori, Masahiko Tsuboi, KIMIYO KATO   +4 more
openalex   +2 more sources

Evaluation of the effect of antiarthritic drugs on the secretion of proteoglycans by lapine chondrocytes using a novel assay procedure. [PDF]

, 1989
S Collier, P. Ghosh
openalex   +1 more source

Advancing preclinical drug evaluation through automated 3D imaging for high-throughput screening with kidney organoids. [PDF]

Biofabrication
Oishi H, Tabibzadeh N, Morizane R.
europepmc   +1 more source

COVID-19 emergency responders in FDA's Center for Drug Evaluation and Research. [PDF]

J Am Pharm Assoc (2003), 2020
Gormley LCA, Ngan CK.
europepmc   +1 more source

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source