Results 261 to 270 of about 1,122,477 (316)
SARS‐CoV‐2 Is Linked to Brain Volume Loss in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective The impact of SARS‐CoV‐2 infection on brain and spinal cord pathology in patients with multiple sclerosis (pwMS) remains unclear. We aimed to describe changes in brain lesion activity and brain and spinal cord volumes following SARS‐CoV‐2 infection.
Tomas Uher +12 more
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EVALUATION OF ANTIEPILEPTIC DRUGS
Archives of Neurology And Psychiatry, 1950TWO PRINCIPAL electric shock methods have been employed for the laboratory appraisal of anticonvulsant drugs: ( a ) the method of Putnam and Merritt 1 and ( b ) that of Toman, Swinyard and Goodman. 2 In the former, the anticonvulsant potency of a compound is determined by its ability to raise the electric shock convulsion threshold in the cat ...
Graham Chen, Charles R. Ensor
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The evaluation of antirheumatic drugs
Current Medical Research and Opinion, 1973SummaryThe available methods of evaluation of an antirheumatic compound in a clinical trial situation are discussed. The techniques of single-blind and double-blind studies are described and their respective merits analysed. Proposed new techniques for the measurement of joint inflammation are reviewed.
W. C. Dick +3 more
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JAMA: The Journal of the American Medical Association, 1977
The third edition of the AMA Drug Evaluations book ( ADE ) has just been published. * The first edition that appeared in 1971 was prepared by the American Medical Association Department of Drugs under the direction of the Association's Council on Drugs.
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The third edition of the AMA Drug Evaluations book ( ADE ) has just been published. * The first edition that appeared in 1971 was prepared by the American Medical Association Department of Drugs under the direction of the Association's Council on Drugs.
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The evaluation of cytotoxic drugs
Cancer Treatment Reviews, 1979SCOPUS: ar.j ; info:eu-repo/semantics ...
Von Hoff, Daniel D.D. +2 more
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Archives of Otolaryngology - Head and Neck Surgery, 1962
The clinical trial of drugs is of the greatest importance in improving medical practice. No matter how carefully a drug may be studied chemically, in tissue culture, or in lower animals, the final test of its efficacy must be made in human beings. Physicians are constantly called upon by drug companies to conduct such trials.
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The clinical trial of drugs is of the greatest importance in improving medical practice. No matter how carefully a drug may be studied chemically, in tissue culture, or in lower animals, the final test of its efficacy must be made in human beings. Physicians are constantly called upon by drug companies to conduct such trials.
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Journal of the American Medical Association, 1958
To the Editor:— The article, "Factors Influencing Clinical Evaluation of Drugs," by Modell and Houde, inThe Journal( 167: 2190-2199 [Aug. 30] 1958) was most interesting and important. However, a most significant factor in the appraisal of drugs should be mentioned in this connection, and that is timing.
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To the Editor:— The article, "Factors Influencing Clinical Evaluation of Drugs," by Modell and Houde, inThe Journal( 167: 2190-2199 [Aug. 30] 1958) was most interesting and important. However, a most significant factor in the appraisal of drugs should be mentioned in this connection, and that is timing.
openaire +2 more sources
Evaluation of drug–drug interactions with fesoterodine
European Journal of Clinical Pharmacology, 2009To assess drug-drug interactions of fesoterodine with cytochrome P450 (CYP) 3A4 inhibitor (ketoconazole), inducer (rifampicin), and substrates (ethinylestradiol and levonorgestrel).Effects of ketoconazole 200 mg twice daily and rifampicin 600 mg twice daily on fesoterodine 8 mg once daily were investigated in CYP2D6 extensive metabolizers (EMs) and ...
Bimal Malhotra +2 more
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