Results 261 to 270 of about 18,950,887 (401)

Strategies to reduce the cancer burden and improve access to effective and affordable cancer interventions in Europe

Molecular Oncology, EarlyView.
Comprehensive cancer centre (CCCs) and CCCs of Excellence (CCCoE) integration in healthcare. Through outreach to surrounding community hospitals, CCCs enable wider access to top‐clinical cancer treatments and care, thereby facilitating the swift enrolment of patients into data‐rich clinical trials (PI‐initiated trials testing new concepts, drug ...
Anton Berns, Ulrik Ringborg, Julio Celis, Bengt Jönsson, Michael Baumann   +4 more
wiley   +1 more source

Donor information in research and drug evaluation with induced pluripotent stem cells (iPSCs). [PDF]

Stem Cell Res Ther, 2020
Orzechowski M, Schochow M, Kühl M, Steger F.   +3 more
europepmc   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Choice and its Evaluation of Antivertigo-drugs

, 1972
Takashi Matsunaga
openalex   +2 more sources

Development of an alcoholic liver disease model for drug evaluation from human induced pluripotent stem cell-derived liver organoids. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Feng Z, Zhou B, Shuai Q, Wei Y, Jin N, Wang X, Zhao H, Liu Z, Xu J, Mu J, Xie J.   +10 more
europepmc   +1 more source

Evaluation of New Drugs

Anesthesia & Analgesia, 1957
openaire   +4 more sources

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

TRANSPORT OF ANTIBACTERIAL DRUGS INTO THE CANINE BLADDER WALL; ITS SIGNIFICANCE IN EVALUATION OF ANTIBACTERIAL DRUGS IN URINE FOR THE TREATMENT OF URINARY TRACT INFECTION

, 1971
Takuzo Adachi
openalex   +2 more sources

Evaluation of drugs for elimination of leukemic cells from the bone marrow of patients with acute leukemia [PDF]

, 1988
ML Auber, LJ Horwitz, A. A. M. Blaauw, S Khorana, Stephen B. Tucker, T Woods, M Warmuth, Dicke Ka, KB McCredie, Gary Spitzer   +9 more
openalex   +1 more source

Rapid Processing and Drug Evaluation in Glioblastoma Patient-Derived Organoid Models with 4D Bioprinted Arrays. [PDF]

iScience, 2020
Chadwick M, Yang C, Liu L, Gamboa CM, Jara K, Lee H, Sabaawy HE.   +6 more
europepmc   +1 more source