Results 21 to 30 of about 18,950,887 (401)

Quality Appraisal of Ambulatory Oral Cephalosporin and Fluoroquinolone Use in the 16 German Federal States from 2014–2019

open access: yesAntibiotics, 2021
Background: Despite concerns about causing bacterial resistance and serious side effects, oral cephalosporins and fluoroquinolones are still frequently prescribed in Germany.
Gabriele Gradl   +4 more
doaj   +1 more source

Withdrawing Approval of Makena - A Proposal from the FDA Center for Drug Evaluation and Research.

open access: yesNew England Journal of Medicine, 2020
Withdrawing Approval of Makena The FDA’s Center for Drug Evaluation and Research has recommended withdrawing the approval of Makena for the prevention of recurrent preterm birth after a trial faile...
Christina Y. Chang   +5 more
semanticscholar   +1 more source

Determination of Modified QuEChERS Method for Chlorothalonil Analysis in Agricultural Products Using Gas Chromatography–Mass Spectrometry (GC-MS/MS)

open access: yesFoods, 2023
Chlorothalonil is an organochlorine fungicide that blocks the respiratory process of cells and persists in agricultural products because it is used extensively to prevent fungal diseases. An analytical method of chlorothalonil using the modified QuEChERS
Da-Young Yun   +4 more
doaj   +1 more source

Evaluation of Increases in Drug Overdose Mortality Rates in the US by Race and Ethnicity Before and During the COVID-19 Pandemic.

open access: yesJAMA psychiatry, 2022
Evaluation of Increases in Drug Overdose Mortality Rates in the US by Race and Ethnicity Before and During the COVID-19 Pandemic Drug overdose mortality rates have increased sharply in the US since the COVID-19 pandemic began in 2020.1 Since 2015 ...
J. Friedman, H. Hansen
semanticscholar   +1 more source

Evaluating the potential of gold, silver, and silica nanoparticles to saturate mononuclear phagocytic system tissues under repeat dosing conditions

open access: yesParticle and Fibre Toxicology, 2017
Background As nanoparticles (NPs) become more prevalent in the pharmaceutical industry, questions have arisen from both industry and regulatory stakeholders about the long term effects of these materials. This study was designed to evaluate whether gold (
James L. Weaver   +19 more
doaj   +1 more source

Evaluation of skin phototoxicity of transdermally administered pharmaceuticals in Sprague-Dawley rats

open access: yesLaboratory Animal Research, 2020
Some drugs cause phototoxicity in humans when exposed to light, thus there is a need for an in vivo phototoxicity test to evaluate them. However, an in vivo phototoxicity test method to evaluate this has not been established.
Nam Hee Youn   +7 more
doaj   +1 more source

Exploring racial disparities in treatment patterns and outcomes for patients with multiple myeloma using real world data

open access: yesBlood Cancer Journal, 2022
This retrospective observational study evaluated racial disparities among Black and White patients with multiple myeloma (MM). We included patients from a longitudinal de-identified EHR-derived database who had ≥2 visits recorded on or after 1/1/2011 ...
Kathleen Maignan   +10 more
doaj   +1 more source

Consideration on the Research and Development of Anti-tumor Bispecific Antibody Drugs

open access: yesChinese Journal of Lung Cancer, 2022
The drugs of programmed cell death 1 and its ligand 1 immune checkpoint inhibitors have ushered in a new era of anti-tumor immunotherapy, which has shown outstanding efficacy in some tumors, such as Hodgkin lymphoma, but there is still low response rate ...
Yuanyuan SONG   +4 more
doaj   +1 more source

Ceftobiprole: drug evaluation and place in therapy

open access: yesExpert Review of Anti-Infective Therapy, 2019
Introduction: Ceftobiprole is a fifth-generation cephalosporin with a broad spectrum of antimicrobial activity, including also methicillin-resistant Staphylococcus aureus (MRSA). Ceftobiprole is approved for the treatment of community-acquired pneumonia (
D. Giacobbe   +10 more
semanticscholar   +1 more source

Robust Sub-nanomolar Library Preparation for High Throughput Next Generation Sequencing

open access: yesBMC Genomics, 2018
Background Current library preparation protocols for Illumina HiSeq and MiSeq DNA sequencers require ≥2 nM initial library for subsequent loading of denatured cDNA onto flow cells.
Wells W. Wu   +7 more
doaj   +1 more source

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