Results 21 to 30 of about 22,118 (189)

MVA vector expression of SARS-CoV-2 spike protein and protection of adult Syrian hamsters against SARS-CoV-2 challenge

open access: yesnpj Vaccines, 2021
Numerous vaccine candidates against SARS-CoV-2, the causative agent of the COVID-19 pandemic, are under development. The majority of vaccine candidates to date are designed to induce immune responses against the viral spike (S) protein, although ...
Clement A. Meseda   +8 more
doaj   +1 more source

The HIT Network for Children and Adolescents With CNS Tumors Facilitates Improvements of Diagnostic Assessments, Multimodal Treatments, Individual Counseling, and Research in Germany, Austria, and Switzerland

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The HIT network was established in 2000 to create a population‐based structure aiming to improve survival rates and reduce late effects for children with central nervous system (CNS) tumors by conducting comprehensive clinical trials.
Stefan Rutkowski   +59 more
wiley   +1 more source

The complete chloroplast genome sequence of three medicinal species; Curcuma longa, Curcuma wenyujin, and Curcuma phaeocaulis (Zingiberaceae)

open access: yesMitochondrial DNA. Part B. Resources, 2021
Curcuma longa, C. wenyujin and C. phaeocaulis are important herbal medicine which of rhizomatous herbaceous perennial plant of the family Zingiberaceae.
Min-Kyeoung Kim   +5 more
doaj   +1 more source

Patient Activation in Childhood, Adolescent, and Young Adult Cancer Survivors: Current Insights and Implications for Survivorship Care—A Systematic Review From the e‐QuoL Project

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Patient activation—encompassing knowledge, confidence, and skills in managing individual's health—is a cornerstone of person‐centered care. However, its significance among childhood, adolescent, and young adult cancer survivors (CAYACS) remains unexplored. This article examines the application of the 13‐item Patient Activation Measure (
Charlotte Demoor‐Goldschmidt   +12 more
wiley   +1 more source

Comparison of commonly used ICR stocks and the characterization of Korl:ICR

open access: yesLaboratory Animal Research, 2017
Mouse is a commonly used animal in life science studies and is classified as outbred if genetically diverse and inbred if genetically homogeneous. Outbred mouse stocks, are used in toxicology, oncology, infection and pharmacology research.
Hye-Jun Shin   +7 more
doaj   +1 more source

Defining the right diluent for intravenous infusion of therapeutic antibodies

open access: yesmAbs, 2020
Therapeutic monoclonal antibodies (mAbs) are commonly administered to patients through intravenous (IV) infusion, which involves diluting the medication into an infusion solution (e.g., saline and 5% dextrose).
Shen Luo   +5 more
doaj   +1 more source

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij   +11 more
wiley   +1 more source

Dual functional POGases from bacteria encompassing broader O-glycanase and adhesin activities

open access: yesNature Communications
Mucin-type O-glycans on glycoproteins are pivotal for biology and impact the quality of biotherapeutics. Furthermore, glycans on host cells serve as ligands for lectins/adhesins on bacteria for bacterium-host interactions in the colonization or ...
Linjiao Zhou   +12 more
doaj   +1 more source

Effects of Cancer Treatment on Somatosensory and Nociceptive Processing in Children and Adolescents: A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Chemotherapy‐induced peripheral neuropathy remains a major complication in pediatric cancer, with disrupted somatosensory and nociceptive processing being a key aspect. This review synthesizes empirical studies on alterations in somatosensory and nociceptive processing in children and adolescents with cancer.
Julia Schweiger   +4 more
wiley   +1 more source

FDA’s new pharmaceutical quality initiative: Knowledge-aided assessment & structured applications

open access: yesInternational Journal of Pharmaceutics: X, 2019
This paper describes a new FDA’s pharmaceutical quality assessment system: Knowledge-aided Assessment & Structured Application (KASA). The KASA system is designed to: 1) capture and manage knowledge during the lifecycle of a drug product; 2) establish ...
Lawrence X. Yu   +5 more
doaj   +1 more source

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