Results 31 to 40 of about 8,240,920 (301)

Dual functional POGases from bacteria encompassing broader O-glycanase and adhesin activities

open access: yesNature Communications
Mucin-type O-glycans on glycoproteins are pivotal for biology and impact the quality of biotherapeutics. Furthermore, glycans on host cells serve as ligands for lectins/adhesins on bacteria for bacterium-host interactions in the colonization or ...
Linjiao Zhou   +12 more
doaj   +1 more source

DKK1 inhibits breast cancer cell migration and invasion through suppression of β-catenin/MMP7 signaling pathway

open access: yesCancer Cell International, 2019
Background DKK1 has been reported to act as a tumor suppressor in breast cancer. However, the mechanism of DKK1 inhibits breast cancer migration and invasion was still unclear.
Jie Niu   +9 more
doaj   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier   +18 more
wiley   +1 more source

Drug Court Process Evaluation Report, February 2008 [PDF]

open access: yes, 2008
The Iowa Consortium for Substance Abuse Research and Evaluation conducted a process evaluation in 2007 on the seven adult and juvenile drug courts existing in Iowa in 2003.

core  

An Independent Evaluation [PDF]

open access: yes, 2021
Population aging—resulting from falling fertility rates, declining mortality, and increased longevity—shapes the profile and the needs of a growing number of countries.
Independent Evaluation Group
core   +1 more source

Selecting an evaluation consultant or team [PDF]

open access: yes, 2012
French version available in IDRC Digital Library: Choix de l’évaluateur ou de l’équipe d'évaluationRegardless of the evaluation topic and intended use, the most important general characteristics to consider when selecting an external evaluator are ...
IDRC. Evaluation Unit
core   +1 more source

Drug usage evaluation of dapsone

open access: yesIndian Journal of Pharmaceutical Sciences, 2009
Dapsone has been the principal drug in a multidrug regimen recommended by the World Health Organization for the treatment of leprosy. It is also widely used by dermatologists in varied skin conditions like dermatitis herpetiformis, bullous pemphigoid, Behcet's disease, lupus erythematous and a host of other skin diseases. Hence an attempt has been made
Kannan, G.   +6 more
openaire   +3 more sources

Safety and Effectiveness of a High‐Dose, Tailored Tissue Plasminogen Activator Therapy Protocol: A Joint Pediatric Hematology and Cardiac ICU Quality Improvement Initiative Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak   +5 more
wiley   +1 more source

Optimized LC–MS/MS method for simultaneous determination of multiclass veterinary anthelmintic residues in animal-derived matrices

open access: yesFood Science of Animal Resources
Anthelmintics are veterinary drugs used to treat or prevent diseases in livestock and fishery products. However, their residues in animal-derived foods pose potential risks to human health. In Korea, maximum residue limits (MRLs) have been established to
Ye-Bin Jang   +4 more
doaj   +1 more source

Evaluation and Prediction of Drug Permeation

open access: yesJournal of Pharmacy and Pharmacology, 1999
Abstract A major challenge confronting the pharmaceutical scientist is to optimize the selective and efficient delivery of new active entities and drug candidates. Successful drug development requires not only optimization of specific and potent pharmacodynamic activity, but also efficient delivery to the target site.
Pagliara, Alessandra   +4 more
openaire   +4 more sources

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