Results 21 to 30 of about 8,629,035 (303)

Evaluation of skin phototoxicity of transdermally administered pharmaceuticals in Sprague-Dawley rats

open access: yesLaboratory Animal Research, 2020
Some drugs cause phototoxicity in humans when exposed to light, thus there is a need for an in vivo phototoxicity test to evaluate them. However, an in vivo phototoxicity test method to evaluate this has not been established.
Nam Hee Youn   +7 more
doaj   +1 more source

Robust Sub-nanomolar Library Preparation for High Throughput Next Generation Sequencing

open access: yesBMC Genomics, 2018
Background Current library preparation protocols for Illumina HiSeq and MiSeq DNA sequencers require ≥2 nM initial library for subsequent loading of denatured cDNA onto flow cells.
Wells W. Wu   +7 more
doaj   +1 more source

Exploring racial disparities in treatment patterns and outcomes for patients with multiple myeloma using real world data

open access: yesBlood Cancer Journal, 2022
This retrospective observational study evaluated racial disparities among Black and White patients with multiple myeloma (MM). We included patients from a longitudinal de-identified EHR-derived database who had ≥2 visits recorded on or after 1/1/2011 ...
Kathleen Maignan   +10 more
doaj   +1 more source

Evaluation of the Peer Support Program (Student Drug Prevention) 1986-1987

open access: yes, 2019
The Peer Support program is a school based program funded by the National Campaign Against Drug Abuse (NCADA) as a drug prevention strategy. Prior to the existence of the NCADA the program was funded through the NSW Drug and Alcohol Authority.
Directorate of the Drug Offensive
core   +1 more source

Enhanced drug treatment service evaluation report [PDF]

open access: yes, 2023
This is the report of a service evaluation of the Enhanced Drug Treatment Service (EDTS), which is a part of Glasgow City Alcohol and Drug Recovery Services (GADRS).
Carter, Daniel   +2 more
core  

Multiplex PCR-based titration (MPBT) assay for determination of infectious titers of the three Sabin strains of live poliovirus vaccine

open access: yesVirology Journal, 2019
Background Conventional assays to titrate polioviruses usually test serial dilutions inoculated into replicate cell cultures to determine a 50% cytopathic endpoint, a process that is both time-consuming and laborious.
Hasmik Manukyan   +5 more
doaj   +1 more source

Advanced therapy medicinal products in China: Regulation and development

open access: yesMedComm, 2023
Advanced therapy medicinal products (ATMPs) have shown dramatic efficacy in addressing serious diseases over the past decade. With the acceleration and deepening of China's drug regulatory reforms, the country sees a continuous introduction of policies ...
Jiaqi Lu, Longchang Xu, Wei Wei, Wu He
doaj   +1 more source

The in vivo revolution in CAR-T therapy medicinal products: challenges and regulatory prospects

open access: yesSignal Transduction and Targeted Therapy
Chimeric antigen receptor T-cell (CAR-T) therapy, a groundbreaking advancement in cancer immunotherapy, has demonstrated remarkable efficacy in treating hematological malignancies and autoimmune diseases.
Jiaqi Lu   +7 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Public feedback to FDA on regulatory considerations for AI in drug manufacturing

open access: yesAAPS Open
FDA’s Center for Drug Evaluation and Research (CDER) established the Framework for Regulatory Advanced Manufacturing Evaluation (FRAME) initiative to establish a regulatory framework to support the adoption of advanced manufacturing technologies that ...
Jayanti Das   +5 more
doaj   +1 more source

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