Results 111 to 120 of about 105,471 (261)

Erratum to “An Updated Review of the Molecular Mechanisms in Drug Hypersensitivity”

open access: yesJournal of Immunology Research, 2019
Chun-Bing Chen   +6 more
doaj   +1 more source

Validation of the Chinese drug hypersensitivity quality of life questionnaire: Role of delabeling. [PDF]

open access: yesAsia Pac Allergy, 2023
Mak HWF   +6 more
europepmc   +1 more source

Confirmation of Fixed Quarterly Riliprubart Regimen in Patients with Cold Agglutinin Disease Using Population PK/PD and Exposure‐Response Analyses

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Riliprubart is a second‐generation, humanized immunoglobulin G4 that inhibits only the activated form of the C1s component of the proximal classical complement pathway. The clinical studies of riliprubart conducted thus far for the treatment of cold agglutinin disease (CAD), a rare autoimmune disease, include a Phase 1 first‐in‐human study in healthy ...
Timothy Chow   +3 more
wiley   +1 more source

HLA-DRB1 is associated with cefaclor-induced immediate hypersensitivity

open access: yesWorld Allergy Organization Journal
Background: Drug-induced hypersensitivity such as anaphylaxis is an important cause of drug-related morbidity and mortality. Cefaclor is a leading cause of drug induced type I hypersensitivity in Korea, but little is yet known about genetic biomarkers to
So-Young Park, MD, PhD   +15 more
doaj  

Synthesis of 19‐Hydroxyarachidonic Acid by Fungal Peroxygenases: An Experimental and Computational Study

open access: yesChemSusChem, Accepted Article.
Hydroxylated derivatives of arachidonic acid play crucial roles in physiology and inflammation response, with distinct biological effects for (R)‐ and (S)‐enantiomers, highlighting their pharmaceutical relevance. Here, we harness recombinant unspecific peroxygenases (UPOs)—from the fungi Coprinopsis cinerea (rCciUPO) and Agrocybe aegerita (rAaeUPO ...
Alejandro González-Benjumea   +7 more
wiley   +1 more source

RESTORATION OF DELAYED HYPERSENSITIVITY IN MICE RECEIVING IMMUNOSUPPRESSIVE DRUGS BY COMETIDINE

open access: bronze, 1985
Ramon L. Zapata-Sirvent   +2 more
openalex   +1 more source

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