Results 111 to 120 of about 223,933 (345)

Drug Hypersensitivity Syndrome toCarbamazepine and Human Herpes Virus 6 Infection: Case Reportand Literature Review [PDF]

, 2018
.: We describe a patient with a drug-induced hypersensitivity syndrome to carbamazepine and a concomitant active infection with human herpes virus 6 (HHV-6).
Battegay, E., Bircher, A., Hirsch, H., Schaub, N., Steffen, I., Zeller, A.   +5 more
core  

β-lactam hypersensitivity involves expansion of circulating and skin-resident Th22 cells [PDF]

, 2017
Background: β-lactam hypersensitivity has been classified according to the phenotype and function of drug-specific T-cells; however, new T-cell subsets have not been considered.
Andrew Sullivan, B. Kevin Park, Baba, Britschgi, Cavani, Chen, Daly, Daniel Peckham, Dean J. Naisbitt, Dietz, Duhen, El-Ghaiesh, Eryi Wang, Eyerich, Eyerich, Faulkner, Fujita, Gaide, Geiger, Hofmann, Homey, John Farrell, Kagami, Kakinuma, Kim, Lee Faulkner, Martin, Mirshafiey, Monshi, Naisbitt, Nassif, Paul Whitaker, Phillips, Picard, Pichler, Pichler, Pirmohamed, Posadas, Rozieres, Sabat, Spanou, Veldhoen, Watanabe, Whitaker, Whitaker, Wuillemin, Yaseen, Yawalkar, Zabel, Zawodniak   +49 more
core   +2 more sources

Overcoming PEG Antigenicity: Statistical PEG Isomers Reduce Antibody Binding

Advanced Science, EarlyView.
Conventional poly(ethylene glycol) (PEG) is commonly applied in biomedicine, but is now known to induce antibody formation. Here, it is shown that the development of “randomized PEG” (rPEG) featuring glycidyl methyl ether (GME) comonomers decreased antibody binding.
Mareike Deuker, Dominik Schulz, Kaloian Koynov, Svenja Morsbach, Holger Frey, Katharina Landfester   +5 more
wiley   +1 more source

Self‐Assembled Myricetin‐Arginine Conjugate Nanozymes for Targeted Suppression of Joint Inflammation and Osteoclastogenesis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong, Penghao Ji, Jinxi An, Junchao Huang, Ziheng Bu, Xudong Zhang, Wei Liu, Tingyu Wu, Sen Wang, Wei Zhu, Yuhui Li, Jixian Wan, Sudan Xu, Minfeng Huo, Peng Wu   +14 more
wiley   +1 more source

Wearable Thermoelectric Generators for In Vivo Modulation of Insulin Release

Advanced Energy Materials, EarlyView.
This work presents a wearable, self‐powered thermoelectric system (IGNITE) that sustainably harvests body heat to electrically stimulate engineered human cells for insulin release. Operating autonomously without batteries, IGNITE achieves glycemic control in diabetic mice, demonstrating a significant advance in bioelectronic medicine and setting the ...
Debasis Maity, Jinbo Huang, Martin Fussenegger   +2 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

Hepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman, Neehar Parikh, Dan J. Clauw, David A. Williams, Elliot B. Tapper   +4 more
wiley   +1 more source

Drug Hypersensitivity [PDF]

World Allergy Organization Journal, 2007
Sima Moghaddasian, Mahin Baradaran Rezaei, Nasrin Mehdipurzare   +2 more
  +6 more sources

Therapeutic Drug Safety, Important to ‘Close the Gap’ for Aboriginal and Torres Strait Islanders: A Case of Phenytoin Hypersensitivity Syndrome [PDF]

, 2018

openalex   +1 more source

Treg Cells Modulate Neuroinflammation and Behavioral Deficits in Autism: Evidence From MR‐Based Genetic Analyses and Experimental Models

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental condition that is increasingly linked to immune dysfunction and neuroinflammation. Regulatory T cells (Tregs), which are crucial in maintaining immune homeostasis, have been implicated in the pathogenesis of ASD.
Zuqing Nie, Xinyi Xu, Junhao Chen, Huiling Chen, Meng Li, Yang Zhang, Zhiwei Li, Chen Shen, Jie Wen, Xia Cao   +9 more
wiley   +1 more source

An 8-Year-Old Girl with Drug Hypersensitivity to First Triptorelin Acetate Administration [PDF]

, 2023
Nayoung Jung, Ji Eun Lee, Dae Hyun Lim, Jeong Hee Kim   +3 more
openalex   +1 more source