Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
Abstract By targeting the underlying etiology, precision therapies offer an exciting paradigm shift to improve the stagnant outcomes of drug‐resistant epilepsies, including developmental and epileptic encephalopathies. Unlike conventional antiseizure medications (ASMs) which only treat the symptoms (seizures) but have no effect on the underlying ...
Shuyu Wang +3 more
wiley +1 more source
Drug hypersensitivity reactions in children in clinical practice: A WAO Statement. [PDF]
Steering Committee Authors +48 more
europepmc +1 more source
Transgenic murine models for the study of drug hypersensitivity reactions linked to HLA-I molecules. [PDF]
Puig M, Norcross MA.
europepmc +1 more source
Composition of allogeneic equine orthobiologics and their repeated intra‐articular administrations
Abstract Background Orthobiologics such as platelet‐rich plasma (PRP) and alpha‐2‐macroglobulin (A2MG) are increasingly used for equine musculoskeletal injuries. However, their composition and safety with repeated allogeneic intra‐articular administration remain poorly investigated.
Yanne Van Reusel +7 more
wiley +1 more source
Management of multiple drug hypersensitivity in a child with very severe aplastic anemia: a case report and therapeutic challenge. [PDF]
Chen M +8 more
europepmc +1 more source
Recognizing Drug Hypersensitivity in Pigmented Skin. [PDF]
Lehloenya RJ +3 more
europepmc +1 more source
Buck Wheat: Nutritional, Bioactive Characteristics, Health Benefits, and Side Effects
ABSTRACT Micronutrient deficits have resulted from an over‐reliance on a small number of cereal crops for food security. The agricultural sector faces severe sustainability issues due to the rapid growth of the world's population and sudden climatic changes.
Momina Farooq +2 more
wiley +1 more source
Utility of Patch Testing, LTT, and HLA Genotyping in Identifying Culprit Drugs and Diagnosing Multiple Drug Hypersensitivity in Definite DRESS: A 10-Year Cohort Study. [PDF]
Ünal D +22 more
europepmc +1 more source
Desensitization for the prevention of drug hypersensitivity reactions. [PDF]
Kang SY, Seo J, Kang HR.
europepmc +1 more source
The data obtained through this review highlight the lack of global consensus among radiotherapy centers on the best topical treatment for radiodermatitis. It indicates that the choice of treatment depends on professional judgment due to the absence of standardized guidelines, pointing to the need for more robust scientific research to develop effective
Tâmara Taynah Medeiros da Silva +8 more
wiley +1 more source

