Results 121 to 130 of about 144,000 (291)
Diagnosing multiple drug hypersensitivity in children
, 2012 Multiple drug hypersensitivity (MDH) has been defined as a hypersensitivity to two or more chemically different drugs. Two types of MDH have been reported: the first one, which develops to different drugs administered simultaneously and the second type ...
Romano, Antonino
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aim Paroxysmal nocturnal haemoglobinuria (PNH) is a rare, acquired haematopoietic stem cell disorder. Crovalimab, a complement C5‐inhibitor, is approved for PNH and can be self‐administered subcutaneously every 4 weeks, offering a more convenient route than intravenous C5‐inhibitors.
Mendy ter Avest +4 more
wiley +1 more source
Altered microbiome of serum exosomes in patients with acute and chronic cholecystitis
BMC MicrobiologyBackground This study aimed to investigate the differences in the microbiota composition of serum exosomes from patients with acute and chronic cholecystitis.
Qing Zhu +8 more
doaj +1 more source
Ceftriaxone‐induced liver injury: Incidence, phenotypic characterization and predictive factors
British Journal of Clinical Pharmacology, EarlyView.Introduction Ceftriaxone is a widely used third‐generation cephalosporin in hospitalized patients. Although generally considered safe, it has been associated with hepatobiliary complications and emerging reports of drug‐induced liver injury (DILI). However, data on its true incidence, phenotypic patterns, and predictors remain limited. This study aimed
Mohamed Hatem +5 more
wiley +1 more source
BMEMat, EarlyView.Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao +4 more
wiley +1 more source
Abacavir and the altered peptide repertoire model: Clinical implications
, 2012 Structural and biochemical studies showing that abacavir binds non-covalently to the floor of the peptide binding groove of HLAB* 5701 with exquisite specificity to alter the self-peptides that load on the molecule to be presented to the immune system ...
Phillips, E., Mallal, S.
core +1 more source
Tackling cancer stemness with nanotechnology in the era of precision medicine
BMEMat, EarlyView.Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo +9 more
wiley +1 more source
Volumetric analysis of root coverage with porcine acellular dermal matrix: Case study
Clinical Advances in Periodontics, EarlyView.Abstract Background Gingival recession is prevalent and often treated with coronally advanced flap plus connective tissue graft (CAF+CTG). Porcine acellular dermal matrix (PADM) offers a donor‐site‐free alternative. Contemporary digital imaging allows minimally invasive, three‐dimensional (3D) soft‐tissue assessment. This case report quantified 3D soft‐
Edgar Daniel Vargas‐Quiroga +4 more
wiley +1 more source
Ten‐year follow‐up of bilateral gingival recession treatment: A case report
Clinical Advances in Periodontics, EarlyView.Abstract Background This work aims to present a 10‐year follow‐up of a young patient who underwent treatment with collagen matrix (CM) combined with enamel matrix derivative (EMD) for bilateral gingival recessions in the maxillary canine region. Methods The patient, a 25‐year‐old woman, presented with bilateral Cairo type 1 recessions.
Luiz C. L. Marques‐Junior +4 more
wiley +1 more source