Stevens-Johnson syndrome (SJS) is a life-threatening disease, which is mainly ascribed to drugs, such as sulfonamides and psychoepileptics. In this article, we present a pediatric case of vancomycin-induced SJS and an alternative diagnostic algorithm ...
You-Cheng Lin+10 more
doaj +1 more source
Antinociceptive effects of lacosamide on spinal neuronal and behavioural measures of pain in a rat model of osteoarthritis. [PDF]
Alterations in voltage-gated sodium channel (VGSC) function have been linked to chronic pain and are good targets for analgesics. Lacosamide (LCM) is a novel anticonvulsant that enhances the slow inactivation state of VGSCs. This conformational state can
Dickenson, AH, Rahman, W
core +1 more source
Simulation and Visualization of Chaos in a Driven Nonlinear Pendulum: An Aid to Introducing Chaotic Systems in Physics [PDF]
The presence of physical systems whose characteristics change in a seemingly erratic manner gives rise to the study of chaotic systems. The characteristics of these systems are due to their hypersensitivity to changes in initial conditions. In order to understand chaotic systems, some sort of simulation and visualization is pertinent.
arxiv
Hypersensitive Transport in Photonic Crystals with Accidental Spatial Degeneracies [PDF]
A localized defect mode in a photonic-layered structure develops nodal points. Placing a thin metallic layer at such a nodal point results in the phenomenon of induced transparency. We demonstrate that if this nodal point is not a point of symmetry, then even a tiny alteration of the permittivity in the vicinity of the defect suppresses the localized ...
arxiv
N. Hama+3 more
semanticscholar +1 more source
BACKGROUND Adverse drug reactions (ADRs) can be divided into pharmacological ADRs (type A) and hypersensitivity reactions (type B). Type B reactions can be further subdivided into immediate (1 h, variable manifestation like exanthema, hepatitis ...
R. Böhm+3 more
semanticscholar +1 more source
Food allergies in pregnant women: a study of prevalence in expecting mothers and association with neonatal outcomes [PDF]
Thesis (M.A.)--Boston UniversityIntroduction: Food allergies, the second most common form of allergic disorders in Western countries, have been on the rise in the US over the past few decades especially in young children.
Seita, Helene M.
core +1 more source
Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation [PDF]
ES-62 is the major secreted protein of the rodent filarial nematode Acanthocheilonema viteae. The molecule contains covalently attached phosphorylcholine (PC) residues, which confer anti-inflammatory properties on ES-62, underpinning the idea that drugs ...
Ahlfors+31 more
core +1 more source
Hypersensitivity to chemotherapeutic drugs for the treatment of neoplasms. Literature review
BACKGROUND. Like any other drug, chemotherapy drugs can cause hypersensitivity reactions and are the third leading cause of drug-induced anaphylaxis deaths in the United States.
S.V. Zaikov+3 more
doaj +1 more source
In Vitro Diagnosis of Immediate Drug Hypersensitivity Anno 2017: Potentials and Limitations
BackgroundFor most physicians, quantification of drug-specific immunoglobulin E (drug-sIgE) antibodies constitutes the primary in vitro measure to document immediate drug hypersensitivity reactions (IDHR).
I. Decuyper+11 more
semanticscholar +1 more source