Results 141 to 150 of about 3,934,714 (308)

Cefoperazone induced hypersensitivity vasculitis

open access: yesIndian Journal of Dermatology, 2009
Cefoperazone has been reported to cause vasculitic complications only once before. Here, we report yet another case of hypersensitivity vasculitis associated with cefoperazone.
Katiyar Subodh, Prakash Shivesh
doaj  

HLA pharmacogenetic markers of drug hypersensitivity from the perspective of the populations of the Greater Middle East [PDF]

open access: yes, 2022
Specific HLA associations with drug hypersensitivity may vary between geographic regions and ethnic groups. There are little to no data related to HLA-drug hypersensitivity on populations who reside in the Greater Middle East (GME), a vast region ...
Afify, Nariman   +5 more
core   +1 more source

Pro and Contra: Provocation Tests in Drug Hypersensitivity

open access: yesInternational Journal of Molecular Sciences, 2017
Drug provocation test (DPT) is the controlled administration of a drug to diagnose immune- or non-immune-mediated drug hypersensitivity and the last step for accurate recognition of drug hypersensitivity reactions when the previous diagnostic evaluations
O. Soyer, U. Sahiner, B. Sekerel
semanticscholar   +1 more source

Clinical application of high throughput molecular screening techniques for pharmacogenomics. [PDF]

open access: yes, 2011
Genetic analysis is one of the fastest-growing areas of clinical diagnostics. Fortunately, as our knowledge of clinically relevant genetic variants rapidly expands, so does our ability to detect these variants in patient samples.
Schrijver, Iris, Wiita, Arun P
core   +1 more source

Immunological Mechanisms of Drug Hypersensitivity

open access: yesCurrent Pharmaceutical Design, 2017
Drug hypersensitivity reactions (DHRs) are adverse drug reactions that may be divided into several categories; namely pharmacologic intolerance, idiosyncratic reactions, pseudo-allergic reactions and allergic reactions. Drug allergic reactions are those DHRs that are mediated by either antibodies or drug-specific T cells. They vary in terms of severity,
Adriana Ariza   +4 more
openaire   +3 more sources

Cutaneous drug hypersensitivity : Immunological and genetic perspective

open access: yesIndian Journal of Dermatology, 2011
Drug hypersensitivity is an unpredictable, immunologically mediated adverse reaction, clustered in a genetically predisposed individual. The role of "hapten concept" in immune sensitization has recently been contested by the "pharmacological interaction"
Kisalay Ghosh   +3 more
doaj   +1 more source

Drug-drug interaction prediction based on co-medication patterns and graph matching [PDF]

open access: yesarXiv, 2019
Background: The problem of predicting whether a drug combination of arbitrary orders is likely to induce adverse drug reactions is considered in this manuscript. Methods: Novel kernels over drug combinations of arbitrary orders are developed within support vector machines for the prediction.
arxiv  

Drug Hypersensitivity and Anaphylaxis in Cancer and Chronic Inflammatory Diseases: The Role of Desensitizations

open access: yesFrontiers in Immunology, 2017
Drug allergy is a rising problem in the twenty-first century which affects all populations and races, children, and adults, and for which the recognition, diagnosis, management, and treatment is still not well standardized. Classical and new chemotherapy
M. Castells
semanticscholar   +1 more source

Model Systems for the Study of Drug Hypersensitivity [PDF]

open access: bronze, 1969
Donald R. Hoffman, Dan H. Campbell
openalex   +1 more source

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