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External vs. Powered Endoscopic Dacryocystorhinostomy With Mitomycin C: A Randomized Study

open access: yesThe Laryngoscope, EarlyView.
In this prospective randomized study, we compared the 12‐month outcomes of external dacryocystorhinostomy (ExDCR) and powered endoscopic dacryocystorhinostomy (EnDCR), with intraoperative mitomycin C administered in both groups. Anatomical success rates were 90.0% and 100%, respectively, while functional success rates were 86.7% and 96.7%.
Michał Kinasz   +3 more
wiley   +1 more source

Drug hypersensitivity reactions: review of the state of the science for prediction and diagnosis. [PDF]

open access: yesToxicol Sci
Pallardy M   +13 more
europepmc   +1 more source

Gene Therapy for Amino Acid Decarboxylase Deficiency: Clinical and Imaging Outcomes in a French Cohort

open access: yesMovement Disorders, EarlyView.
Abstract Background Intracerebral gene therapy is effective for amino acid decarboxylase (AADC) deficiency, but relationships between anatomical putaminal coverage, metabolic dynamics, and clinical recovery remain poorly understood. Objectives Assess safety, long‐term efficacy, and clinical–radiological correlations in a genetically diverse European ...
Clément Dunoyer   +27 more
wiley   +1 more source

Evaluation of the frequency and characteristics of drug hypersensitivity reactions in hospitalized children: Real life-cohort study. [PDF]

open access: yesWorld Allergy Organ J
Büyük Yaytokgil Ş   +8 more
europepmc   +1 more source

Clues of HLAs, metabolic SNPs, and epigenetic factors in T cell-mediated drug hypersensitivity reactions. [PDF]

open access: yesHeliyon
Molatefi R   +10 more
europepmc   +1 more source

Drug Hypersensitivity: Flare-Up Reactions, Cross-Reactivity and Multiple Drug Hypersensitivity

open access: yesJournal of Dermatology, 2011
In drug hypersensitivity, change of drug treatment and continuation with a new drug may result in reappearance of drug hypersensitivity symptoms. This is not uncommon in patients with chronic infections requiring continued and long-lasting antibiotic ...
Werner J. Pichler, Barbara Daubner
exaly   +2 more sources
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Pathophysiology of drug hypersensitivity

British Journal of Clinical Pharmacology, 2023
Drug hypersensitivity reactions (DHRs) are type B adverse drug reactions (ADRs) traditionally defined as unpredictable, dose independent and not related to the drug pharmacology. DHRs, also called drug allergy if the immune system involvement is confirmed, represent around one‐sixth of all ADRs and can cause major clinical problems due to their vague ...
Abdelbaset A. Elzagallaai   +1 more
openaire   +2 more sources

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