Results 51 to 60 of about 3,996,783 (390)

HLA Associations and Clinical Implications in T-Cell Mediated Drug Hypersensitivity Reactions: An Updated Review

Journal of Immunology Research, 2014
T-cell mediated drug hypersensitivity reactions may range from mild rash to severe fatal reactions. Among them, drug reaction with eosinophilia and systemic symptoms (DRESS) or drug-induced hypersensitivity syndrome (DIHS), Stevens-Johnson syndrome ...
Chi-Yuan Cheng, Shih-Chi Su, Chi-Hua Chen, Wei-Li Chen, Shin-Tarng Deng, Wen-Hung Chung   +5 more
doaj   +1 more source

Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial [PDF]

, 2004
Background: Patients with irritable bowel syndrome (IBS) often feel they have some form of dietary intolerance and frequently try exclusion diets. Tests attempting to predict food sensitivity in IBS have been disappointing but none has utilised IgG ...
Atkinson, W., Shaath, N., Sheldon, T.A., Whorwell, P.J.   +3 more
core   +3 more sources

A Novel System to Diagnose Cutaneous Adverse Drug Reactions Employing the Cellscan—Comparison with Histamine Releasing Test and Inf-γ Releasing Test

Clinical and Developmental Immunology, 2005
Background: There are several mechanisms to describe allergic drug reactions yet the methods to diagnose them are limited.
Ilan Goldberg, Boris Gilburd, Martine Szyper Kravitz, Shmuel Kivity, Berta Ben Chaim, Tirza Klein, Yael Schiffenbauer, Ela Trubniykovr, Sarah Brenner, Yehuda Shoenfeld   +9 more
doaj   +1 more source

Mas-related G-protein–coupled receptors inhibit pathological pain in mice [PDF]

, 2010
An important objective of pain research is to identify novel drug targets for the treatment of pathological persistent pain states, such as inflammatory and neuropathic pain.
Altier, Baron, Basbaum, Cai, Calignano, Callaghan, Caterina, Chen, Chen, Coderre, Costigan, Costigan, D. J. Anderson, De Felipe, Delmas, Dong, Gerevich, Guan, Guan, Herrero, Honan, Ikeda, Julius, Knabl, Kusudo, Lembo, Li, Li, Liu, Liu, Lu, MacDermott, MacPherson, Malmberg, Melzack, Melzack, Miraucourt, Ndong, Neumann, Q. Liu, Rau, Rodriguez Parkitna, S. N. Raja, Scholz, Seal, Woolf, X. Dong, Y. Guan, Z. Tang, Zeng   +49 more
core   +2 more sources

Biomarkers of immediate drug hypersensitivity

Allergy, 2023
AbstractImmediate drug hypersensitivity reactions (IDHRs) are a burden for patients and the health systems. This problem increases when taking into account that only a small proportion of patients initially labelled as allergic are finally confirmed after an allergological workup.
Cristobalina Mayorga, Adriana Ariza, Rosa Muñoz‐Cano, Vito Sabato, Inmaculada Doña, Maria J. Torres   +5 more
openaire   +5 more sources

EAACI position paper on how to classify cutaneous manifestations of drug hypersensitivity

Allergy. European Journal of Allergy and Clinical Immunology, 2018
Drug hypersensitivity reactions (DHRs) are common, and the skin is by far the most frequently involved organ with a broad spectrum of reaction types. The diagnosis of cutaneous DHRs (CDHR) may be difficult because of multiple differential diagnoses.
K. Brockow, M. Ardern-Jones, M. Mockenhaupt, W. Aberer, A. Barbaud, J. Caubet, R. Spiewak, M. Torres, C. Mortz   +8 more
semanticscholar   +1 more source

Clinical Characteristics and Disease Burden of Patients with Moderate-to-Severe Generalized Pustular Psoriasis Flares in Taiwan

Dermatology and Therapy
Introduction Generalized pustular psoriasis (GPP) is a rare and severe psoriasis subtype characterized by the rapid onset of coalescing sterile pustules over broad body areas and systemic inflammation.
Chun-Wei Lu, Chien-Yu Tseng, Chuang-Wei Wang, Shang-Hung Lin, Chun-Bing Chen, Rosaline Chung-Yee Hui, Ching-Chi Chi, Yu-Huei Huang, Chih-Hung Lee, Fang-Ju Lin, Wen-Hung Chung   +10 more
doaj   +1 more source

The Mechanism of Onychomadesis (Nail Shedding) and Beau’s Lines Following Hand-Foot-Mouth Disease

Viruses, 2019
Background: Nail changes, including onychomadesis (nail shedding) and Beau’s line, following hand-foot-mouth disease (HFMD) are a common emergence at the stage of late complications of HFMD. However, the exact mechanism is still unknown. Therefore,
Hsiu-Hui Chiu, Ming-Tsan Liu, Wen-Hung Chung, Yu-Shien Ko, Chin-Fang Lu, Cheng-Che E. Lan, Chun-Wei Lu, Kai-Che Wei   +7 more
doaj   +1 more source

Acute coronary syndrome in diclofenac sodium-induced type I hypersensitivity reaction : Kounis syndrome [PDF]

, 2007
Drug-induced type I hypersensitivity reactions are frequent. Sometimes, acute coronary syndrome (ACS) can be registered in such patients, which may have a serious impact on the course and management of the allergic reaction.
Gluvic, Zoran M., Jankovic-Gavrilovic, Jelena, Panic, Milos, Putnikovic, Biljana, Rasic-Milutinovic, Zorica, Stojkovic, Aleksandra   +5 more
core  

Understanding alcoholics’ “difficulty in life”: An empirical comparison of alcoholics and nonalcoholics

, 2017
The Japanese success rate for alcoholism treatment is approximately 30%, indicating high relapse rates. Although “difficulty in life” is thought to contribute to alcoholics’ relapse, the characteristics of the phenomenon are unknown.
Ito, Keiko
core   +3 more sources