Results 51 to 60 of about 3,966,363 (347)

Chronic Opioids in Gout: A Matched Cohort Study from the Veteran's Health Administration

Arthritis Care &Research, Accepted Article.
Objective Though used frequently to treat flare, risk of chronic opioid exposure in gout has not been well defined. In this study, we examined the hypothesis that people with gout are more likely than individuals without gout to be prescribed chronic opioids over time.
Lindsay N. Helget, Bryant R. England, Punyasha Roul, Harlan Sayles, Tuhina Neogi, James R. O'Dell, Joshua F. Baker, Ted R. Mikuls   +7 more
wiley   +1 more source

Recent Development and Clinical Application of Cancer Vaccine: Targeting Neoantigens

Journal of Immunology Research, 2018
Recently, increasing data show that immunotherapy could be a powerful weapon against cancers. Comparing to the traditional surgery, chemotherapy or radiotherapy, immunotherapy more specifically targets cancer cells, giving rise to the opportunities to ...
Ren-You Pan, Wen-Hung Chung, Mu-Tzu Chu, Shu-Jen Chen, Hua-Chien Chen, Lei Zheng, Shuen-Iu Hung   +6 more
doaj   +1 more source

Exploring patients’ profiles associated with the resolution of acute calcium pyrophosphate arthritis treatedwith colchicine and prednisone: post hoc analysis of a randomized controlled trial

Arthritis Care &Research, Accepted Article.
Objective The objective was to identify factors determining acute arthritis resolution and safety with colchicine and prednisone in acute calcium pyrophosphate (CPP) crystal arthritis. Methods We conducted a post hoc analysis of the COLCHICORT trial, which compared colchicine and prednisone for the treatment of acute CPP crystal arthritis, using a ...
Tristan Pascart, Laurène Norberciak, Pascal Richette, Pierre Robinet, Aurore Pacaud, Gauthier Marchasson, Thibault Rabin, Hélène Luraschi, Pierre Maciejasz, Anne‐France Georgel, Augustin Latourte, Hang‐Korng Ea, Sébastien Ottaviani, Charlotte Jauffret, Vincent Ducoulombier   +14 more
wiley   +1 more source

Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis

Arthritis Care &Research, EarlyView.
Objective Up to 40% of patients with inflammatory arthritis (IA) experience persistent pain, traditionally thought to be associated with a shift from peripherally to centrally mediated pain during the disease course in some patients. We assessed sensory profiles of recently diagnosed individuals with IA, hypothesizing that pain reported at this early ...
Zoe Rutter‐Locher, Sam Norton, Joseph L. Taylor, Bina Menon, Tom Esterine, Ruth Williams, Leonie S. Taams, Kirsty Bannister, Bruce W. Kirkham   +8 more
wiley   +1 more source

Drug hypersensitivity in students from São Paulo, Brazil

Clinics, 2010
BACKGROUND: Drug hypersensitivity is responsible for substantial mortality and morbidity, and increased health costs. However, epidemiological data on drug hypersensitivity in general or specific populations are scarce.
Luis Felipe Chiaverini Ensina, Maria Helena Lopes Amigo, Thais Koch, Evelyn Guzman, Renata Paoli, Inês Cristina Camelo Nunes   +5 more
doaj   +1 more source

Treatment and management of hypersensitivity reactions developed against anti-tuberculosis drug

International Journal of Mycobacteriology, 2022
Background: The World Health Organization Global Tuberculosis Report 2021 defines tuberculosis as the second infectious disease that causes sickness and death after COVID 19 and ranks it as the 13th among the global causes of death.
Zeynep Yegin Katran, Ismet Bulut, Aylin Babalik, Metin Keren   +3 more
doaj   +1 more source

The complexity of drug hypersensitivity reactions [PDF]

Allergy, 2020
Drug hypersensitivity reactions (DHRs) represent a global threat to healthcare systems due to their incidence, with a significant increase over last years.
openaire   +6 more sources

The Genetics of Drug Hypersensitivity Reactions [PDF]

Journal of Investigational Allergology and Clinical Immunology, 2016
DHRs are induced by various mechanisms and encompass a heterogeneous set of potentially life-threatening clinical entities. In addition to environmental effects, individual factors play a key role in this intricate puzzle. However, despite commendable efforts in recent years to identify individual predisposing factors, our knowledge of the genetic ...
Cornejo-García, J A, Jurado-Escobar, R, Doña, I, Perkins, J R, Agúndez, J A, García-Martín, E, Viguera, E, Blanca-López, N, Canto, G, Blanca, M   +9 more
openaire   +4 more sources

Antibody‐Programmable Bimetallic Nanozymes for Transcriptional Blockade Therapy in HER2/ER‐Positive Breast Cancer

Advanced Functional Materials, EarlyView.
Zr‐Fe MOF@Ribociclib@Herceptin (ZFRH) efficiently targets/kills Human Epidermal Growth Factor Receptor 2/Estrogen Receptor‐positive (HER2/ER+) breast cancer cells. It combats tumors by: 1) Elevating ROS, altering redox balance; 2) Inhibiting transcription; 3) Inducing pyroptosis.
Hongkun Miao, Tong Ye, Mingjiang Liu, Jingchao Gao, Lian Tan, Qian Dong, Qingbo Lv, Qianqian Ye, Yu Wang   +8 more
wiley   +1 more source

Efficacy and safety of indigo naturalis oil extract (Lindioil ointment) for the treatment of atopic dermatitis: a randomized, crossover, evaluator-blinded, controlled trial

Frontiers in Pharmacology
IntroductionLindioil ointment or its compound formulations are commonly used traditional Chinese medicine practitioners to treat adult eczema or localized dermatitis.
Chin-Yi Yang, Chin-Yi Yang, Chin-Yi Yang, Chin-Yi Yang, Chun-Bing Chen, Chun-Bing Chen, Chun-Bing Chen, Chun-Bing Chen, Chun-Wei Lu, Chun-Wei Lu, Chun-Wei Lu, Min-Hui Chi, Min-Hui Chi, Min-Hui Chi, Min-Hui Chi, Jennifer Wu, Jennifer Wu, Jennifer Wu, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Wen-Hung Chung, Be-Han Lee, Yin-Ku Lin, Yin-Ku Lin   +24 more
doaj   +1 more source