Results 121 to 130 of about 1,989,460 (302)

Análise da distribuição de tensões em implantes dentários de PEEK pelo método de elementos finitos 3D [PDF]

open access: yes, 2008
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Odontologia.O PEEK vem se mostrando um excelente material na substituição do titânio em aplicações ortopédicas.
Sarot, João Rodrigo
core  

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Ohio BWC Drug-Free EZ Program : technical assistance manual : reference/resource guide

open access: yes, 2002
Title from title screen (viewed Sept. 24, 2004).; "BWC-7648 (Rev. 7/18/2002)"--Screen 87 (i.e. p. 1 of form: Progress report, Drug-Free Workplace/Drug-Free EZ Program).; Electronic text (pdf, 89 p.).; Harvested from the web on 9/24 ...
Drug-Free EZ Program (Ohio. Bureau of Workers' Compensation)
core  

Drug consumption rooms in Europe: Organisational overview. [PDF]

open access: yes, 2014
This report provides an overview of the organisation and working methods of drug consumption rooms (DCRs) in Europe. It offers information about the functioning of DCRs as well as on the organisation and structure of such facilities and aims to benefit ...
Woods, Sara
core  

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Nitric oxide-generating metallic wires for enhanced metal implants

open access: yesCommunications Materials
Metallic implants are integral in modern medicine, offering excellent biocompatibility and mechanical properties. However, implant-related infections pose a major challenge. Current drug delivery methods, such as surface-coated and drug-eluting implants,
Federico Mazur   +6 more
doaj   +1 more source

Light-responsive in situ forming injectable implants for effective drug delivery to the posterior segment of the eye

open access: yes, 2016
Introduction: Frequent intravitreal injections are currently the preferred treatment method for diseases affecting the posterior segment of the eye.
Rupenthal, Ilva   +4 more
core   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

open access: yesFEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima   +8 more
wiley   +1 more source

The Advances in Phospholipids-Based Phase Separation Gels for the Sustained Release of Peptides, Proteins, and Chemotherapeutics

open access: yesPharmaceutics
Implantable drug delivery systems formed upon injection offer a host of advantages, including localized drug administration, sustained release, minimized side effects, and enhanced patient compliance.
Jianxia Dong   +8 more
doaj   +1 more source

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