Results 31 to 40 of about 151,635 (354)

Construction of Local Drug Delivery System on Titanium-Based Implants to Improve Osseointegration

open access: yesPharmaceutics, 2022
Titanium and its alloys are the most widely applied orthopedic and dental implant materials due to their high biocompatibility, superior corrosion resistance, and outstanding mechanical properties.
Fanying Meng   +4 more
doaj   +1 more source

The improved antitumor efficacy of continuous intratumoral chemotherapy with cisplatin-loaded implants for the treatment of sarcoma 180 tumor-bearing mice

open access: yesDrug Delivery, 2019
Cisplatin is the most commonly used antitumor drug in the chemotherapy of a variety of malignancies. However, the severe side effects and drug resistance limit its clinical application.
Li Gao   +9 more
doaj   +1 more source

In vitro–in vivo evaluation of poly(2-hydroxyethyl methacrylate-co-methyl methacrylate) hydrogel implants containing cisplatin

open access: yesActa Pharmaceutica Sinica B, 2011
The aim of this study was to prepare hydrogel disc implants containing cisplatin from hydroxyethyl methacrylate (HEMA) and methyl methacrylate (MMA).
Madhu Babu   +3 more
doaj   +1 more source

Titanium Implants and Local Drug Delivery Systems Become Mutual Promoters in Orthopedic Clinics

open access: yesNanomaterials, 2021
Titanium implants have always been regarded as one of the gold standard treatments for orthopedic applications, but they still face challenges such as pain, bacterial infections, insufficient osseointegration, immune rejection, and difficulty in ...
Xiao Ma   +9 more
doaj   +1 more source

Nanoroughness, Surface Chemistry and Drug Delivery Control by Atmospheric Plasma Jet on Implantable Devices [PDF]

open access: yes, 2018
Implantable devices need specific tailored surface morphologies and chemistries to interact with the living systems or to actively induce a biological response also by the release of drugs or proteins.
Ambrosi, Emmanuele   +8 more
core   +3 more sources

Polysaccharide Based Implantable Drug Delivery: Development Strategies, Regulatory Requirements, and Future Perspectives

open access: yesPolysaccharides, 2022
Implantable drug delivery systems advocate a wide array of potential benefits, including effective administration of drugs at lower concentrations and fewer side-effects whilst increasing patient compliance.
Sagar Salave   +7 more
doaj   +1 more source

Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients

open access: yesNanomaterials, 2021
Dental implants are used broadly in dental clinics as the most natural-looking restoration option for replacing missing or highly diseased teeth. However, dental implant failure is a crucial issue for diabetic patients in need of dentition restoration ...
Renjini Vijay   +6 more
doaj   +1 more source

Widening use of dexamethasone implant for the treatment of macular edema [PDF]

open access: yes, 2017
Sustained-release intravitreal 0.7 mg dexamethasone (DEX) implant is approved in Europe for the treatment of macular edema related to diabetic retinopathy, branch retinal vein occlusion, central retinal vein occlusion, and non-infectious uveitis.
Avitabile T.   +9 more
core   +2 more sources

Implantable Drug Delivery Systems

open access: yesHimalayan Journal of Health Sciences, 2023
Traditional drug delivery methods provide very little, if any, control over the timing and pattern of drug release Medication concentration absorption at the point of action. Undefined medication concentration in plasma is a typical and obvious issue with the traditional dose method.
Golla VenakataSai   +6 more
openaire   +1 more source

Functionalisation of Ti6Al4V and hydroxyapatite surfaces with combined peptides based on KKLPDA and EEEEEEEE peptides [PDF]

open access: yes, 2017
Surface modifications are usually performed on titanium alloys to improve osteo-integration and surface bioactivity. Modifications such as alkaline and acid etching, or coating with bioactive materials such as hydroxyapatite, have previously been ...
Ben-Nissan, Besim   +4 more
core   +6 more sources

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