Results 21 to 30 of about 1,989,460 (302)
Pensando em melhorar a qualidade de vida dos pacientes com doenças do humor vítreo, os oftalmologistas começaram a utilizar recentemente implantes biodegradáveis com corticoide.
André Coura Perez +8 more
doaj +1 more source
Biodistribution of etoposide via intratumoral chemotherapy with etoposide-loaded implants
Etoposide (VP16) is the traditional antitumor agent which has been widely used in a variety of cancers. However, intravenous administration of VP16 was limited in clinical application because of its low aqueous solubility, poor bioavailability and dose ...
Chunsheng Wu +7 more
doaj +1 more source
The visual impairment that often leads to blindness causes a higher morbidity rate. The goal of this work is to create a novel biodegradable polymeric implant obtained from coaxial fibers containing the dispersed drug—acetazolamide—in order to achieve ...
Mariana Morais +2 more
doaj +1 more source
Radiolabeled Risperidone microSPECT/CT Imaging for Intranasal Implant Studies Development
The use of intranasal implantable drug delivery systems has many potential advantages for the treatment of different diseases, as they can provide sustained drug delivery, improving patient compliance.
Jon Ander Simón +9 more
doaj +1 more source
Enhanced osseointegration of drug eluting nanotubular dental implants: An in vitro and in vivo study
Faster and predictable osseointegration is crucial for the success of dental implants, especially in patients with compromised local or systemic conditions. Despite various surface modifications on the commercially available Titanium (Ti) dental implants,
Pankaj Chauhan +15 more
doaj +1 more source
Pharmacodynamics and pharmacokinetics of PLGA-based doxorubicin-loaded implants for tumor therapy
The traditional systemic chemotherapy through intravenous infusion of doxorubicin (DOX) has many side effects. The aim of this study was to develop a PLGA-based DOX-loaded implant and to evaluate the efficacy and drug metabolism distribution of the ...
Peng He +8 more
doaj +1 more source
Dental implants are, nowadays, established surgical devices for the restoration of lost teeth. Considered as an alternative for traditional prosthetic appliances, dental implants surpass them in reliability and patient feedback.
Piotr Wychowański +10 more
doaj +1 more source
The usage of 3D-printing for drug-eluting implants combines the advantages of a targeted local drug therapy over longer periods of time at the precise location of the disease with a manufacturing technique that easily allows modifications of the implant ...
Vanessa Domsta, Anne Seidlitz
doaj +1 more source
Osseointegration of zirconia implants compared with titanium : an in vivo study [PDF]
Background Titanium and titanium alloys are widely used for fabrication of dental implants. Since the material composition and the surface topography of a biomaterial play a fundamental role in osseointegration, various chemical and physical surface ...
Ulrich Meyer +19 more
core +2 more sources
Lipidic nanocapsule drug delivery : neuronal protection for cochlear implant optimization [PDF]
Objective: Sensorineural hearing loss leads to the progressive degeneration of spiral ganglion cells (SGC). Next to postoperative fibrous tissue growth, which should be suppressed to assure a close nerve–electrode interaction, the density of healthy SGC ...
Meyer, Hartwig +15 more
core +1 more source

