Results 11 to 20 of about 1,989,460 (302)

Construction of Local Drug Delivery System on Titanium-Based Implants to Improve Osseointegration

open access: yesPharmaceutics, 2022
Titanium and its alloys are the most widely applied orthopedic and dental implant materials due to their high biocompatibility, superior corrosion resistance, and outstanding mechanical properties.
Fanying Meng   +4 more
doaj   +2 more sources

Development of a Self-assembly Technique for Drug-Delivering Hydroxyapatite Coatings for Ti-Based Implants [PDF]

open access: yes, 2010
PhD 2010 QMTo facilitate the long term osteointegration of Ti implants of various forms, methods aiming to facilitate hydroxyapatite deposition and enhance its adhesion to the Ti surfaces have to be developed.
Ajami, Elnaz
core   +4 more sources

Characterization of drug-release kinetics in trabecular bone from titania nanotube implants [PDF]

open access: yesInternational Journal of Nanomedicine, 2012
Moom Sinn Aw,1 Kamarul A Khalid,2,3 Karan Gulati,1 Gerald J Atkins,2 Peter Pivonka,4 David M Findlay,2 Dusan Losic11School of Chemical Engineering, 2Discipline of Orthopaedics and Trauma, The University of Adelaide, Adelaide, SA, Australia; 3Department ...
Aw MS   +6 more
doaj   +3 more sources

Fabrication and Characterisation of 3D-Printed Triamcinolone Acetonide-Loaded Polycaprolactone-Based Ocular Implants

open access: yesPharmaceutics, 2023
Triamcinolone acetonide (TA) is a corticosteroid that has been used to treat posterior segment eye diseases. TA is injected intravitreally in the management of neovascular disorders; however, frequent intravitreal injections result in many potential side
Febri Annuryanti   +5 more
doaj   +1 more source

Pharmacokinetic Study of Islatravir and Etonogestrel Implants in Macaques

open access: yesPharmaceutics, 2023
The prevention of HIV and unintended pregnancies is a public health priority. Multi-purpose prevention technologies capable of long-acting HIV and pregnancy prevention are desirable for women. Here, we utilized a preclinical macaque model to evaluate the
Michele B. Daly   +18 more
doaj   +1 more source

Biomaterials in cochlear implants [PDF]

open access: yes, 2011
The cochlear implant (CI) represents, for almost 25 years now, the gold standard in the treatment of children born deaf and for postlingually deafened adults.
Lenarz, T   +3 more
core   +1 more source

3D-printed implantable devices with biodegradable rate-controlling membrane for sustained delivery of hydrophobic drugs

open access: yesDrug Delivery, 2022
Implantable drug delivery systems offer an alternative for the treatments of long-term conditions (i.e. schizophrenia, HIV, or Parkinson’s disease among many others).
Camila J. Picco   +7 more
doaj   +1 more source

Lipid implants for controlled release of proteins [PDF]

open access: yes, 2007
In recent years, we have seen significant progress towards understanding the role of proteins in both physiological and pathological processes. Especially neurotrophic factors have increasingly come into focus for the treatment of neurodegenerative ...
Könnings, Stephanie
core   +1 more source

Microimaging of a novel intracochlear drug delivery device in combination with cochlear implants in the human inner ear [PDF]

open access: yes, 2021
The effective delivery of drugs to the inner ear is still an unmet medical need. Local controlled drug delivery to this sensory organ is challenging due to its location in the petrous bone, small volume, tight barriers, and high vulnerability.
Lehner, E.   +17 more
core   +1 more source

How bulk fluid renewal can affect in vitro drug release from PLGA implants: Importance of the experimental set-up

open access: yesInternational Journal of Pharmaceutics: X, 2022
The aim of this study was to better understand the potential impact of partial vs. complete renewal of the bulk fluid during drug release measurements from poly (lactic-co-glycolic acid) (PLGA)-based implants.
C. Bassand   +5 more
doaj   +1 more source

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