Results 31 to 40 of about 1,989,460 (302)

Characterization and in vitro release of cyclosporine-A from poly(D,L-lactide-co-glycolide implants obtained by solvent/extraction evaporation

Química Nova, 2012
Cyclosporine-A-loaded PLGA implants were developed intended for ocular route. Implants were prepared using solvent extraction/evaporation technique followed by casting of the cake into rods in a heated surface. XRD patterns showed that cyclosporine-A was
Juliana Barbosa Saliba, Armando da Silva-Cunha Junior, Gisele Rodrigues da Silva, Maria Irene Yoshida, Alexandra Ancelmo Piscitelli Mansur, Herman Sander Mansur   +5 more
doaj   +1 more source

Osseointegration of zirconia implants : an SEM observation of the bone-implant interface [PDF]

, 2008
Background The successful use of zirconia ceramics in orthopedic surgery led to a demand for dental zirconium-based implant systems. Because of its excellent biomechanical characteristics, biocompatibility, and bright tooth-like color, zirconia ...
Lammers, Lydia, Zipprich Holger, Meyer Ulrich, Mahn Eduardo, Kübler, Norbert, Zipprich, Holger, Meyer, Ulrich, Mahn, Eduardo, Lammers Lydia, Handschel, Jörg, Ommerborn Michelle, Wiesmann Hans-Peter, Depprich Rita, Kübler Norbert R, Depprich, Rita, Ommerborn, Michelle, Naujoks Christian, Naujoks, Christian, Handschel Jörg, Wiesmann, Hans-Peter   +19 more
core   +1 more source

The improved antitumor efficacy of continuous intratumoral chemotherapy with cisplatin-loaded implants for the treatment of sarcoma 180 tumor-bearing mice

Drug Delivery, 2019
Cisplatin is the most commonly used antitumor drug in the chemotherapy of a variety of malignancies. However, the severe side effects and drug resistance limit its clinical application.
Li Gao, Shang Cai, Awei Cai, Yang Zhao, Tangbing Xu, Yan Ma, Yan Xu, Yuan Wang, Hao Wang, Yong Hu   +9 more
doaj   +1 more source

In vitro–in vivo evaluation of poly(2-hydroxyethyl methacrylate-co-methyl methacrylate) hydrogel implants containing cisplatin

Acta Pharmaceutica Sinica B, 2011
The aim of this study was to prepare hydrogel disc implants containing cisplatin from hydroxyethyl methacrylate (HEMA) and methyl methacrylate (MMA).
Madhu Babu, Hemant K.S. Yadav, Afrasim Moin, Hosakote G. Shivakumar   +3 more
doaj   +1 more source

Titanium Implants and Local Drug Delivery Systems Become Mutual Promoters in Orthopedic Clinics

Nanomaterials, 2021
Titanium implants have always been regarded as one of the gold standard treatments for orthopedic applications, but they still face challenges such as pain, bacterial infections, insufficient osseointegration, immune rejection, and difficulty in ...
Xiao Ma, Yun Gao, Duoyi Zhao, Weilin Zhang, Wei Zhao, Meng Wu, Yan Cui, Qin Li, Zhiyu Zhang, Chengbin Ma   +9 more
doaj   +1 more source

Polysaccharide Based Implantable Drug Delivery: Development Strategies, Regulatory Requirements, and Future Perspectives

Polysaccharides, 2022
Implantable drug delivery systems advocate a wide array of potential benefits, including effective administration of drugs at lower concentrations and fewer side-effects whilst increasing patient compliance.
Sagar Salave, Dhwani Rana, Amit Sharma, K. Bharathi, Raghav Gupta, Shubhangi Khode, Derajram Benival, Nagavendra Kommineni   +7 more
doaj   +1 more source

Carbon Nanomaterials Modified Biomimetic Dental Implants for Diabetic Patients

Nanomaterials, 2021
Dental implants are used broadly in dental clinics as the most natural-looking restoration option for replacing missing or highly diseased teeth. However, dental implant failure is a crucial issue for diabetic patients in need of dentition restoration ...
Renjini Vijay, Jayanti Mendhi, Karthika Prasad, Yin Xiao, Jennifer MacLeod, Kostya (Ken) Ostrikov, Yinghong Zhou   +6 more
doaj   +1 more source

Local penetration of doxorubicin via intrahepatic implantation of PLGA based doxorubicin-loaded implants

Drug Delivery, 2019
Doxorubicin (DOX) is widely used in the chemotherapy of a wide range of cancers. However, intravenous administration of DOX causes toxicity to most major organs which limits its clinical application.
Li Gao, Qingshan Li, Jie Zhang, Yixin Huang, Lin Deng, Chenyang Li, Guangping Tai, Banfeng Ruan   +7 more
doaj   +1 more source

Review on Implantable Drug Delivery System

International Journal of Advanced Research in Science, Communication and Technology, 2023
In the past, medications were commonly given orally in the form of liquids or powders. However, to address the challenges associated with oral drug administration, alternative dosage forms were developed. Over time, the need arose for drug delivery systems capable of providing a consistent release of medication directly to the site of action.
null Rajlaxmi Deolekar, null Vaibhavi A. Kalambe, null Bilal Sufi, null Vaibhav Urade   +3 more
openaire   +1 more source

Translational status of biomedical Mg devices in China

Bioactive Materials, 2019
Magnesium (Mg) and its alloys as temporary medical implants with biodegradable and properly mechanical properties have been investigated for a long time.
Yu Sun, Hongliu Wu, Wenhui Wang, Rui Zan, Hongzhou Peng, Shaoxiang Zhang, Xiaonong Zhang   +6 more
doaj   +1 more source