Results 21 to 30 of about 61,983 (302)
Pharmaceutics, 2023 Nanoparticles have numerous applications as drug carriers in drug delivery. The aim of the study was to produce tamoxifen nanoparticles with a defined size and higher encapsulation for efficient tissue uptake with controlled drug release.
Muzna Ali Khattak +13 more
doaj +1 more source
Toward a Lockean Unification of Formal and Traditional Epistemology [PDF]
, 2022 Can there be knowledge and rational belief in the absence of a rational degree of confidence? Yes, and cases of "mistuned knowledge" demonstrate this. In this paper we leverage this normative possibility in support of advancing our understanding of the ...
Lee, Matthew Brandon, Silva Jr, Paul
core
Mucin-Protected Caco-2 Assay to Study Drug Permeation in the Presence of Complex Biorelevant Media
Pharmaceutics, 2022 The poor solubility and permeability of compounds beyond Lipinski’s Rule of Five (bRo5) are major challenges for cell-based permeability assays. Due to their incompatibility with gastrointestinal components in biorelevant media, the exploration of ...
Dong Ye +9 more
doaj +1 more source
Preferred antiretroviral drugs for the next decade of scale up [PDF]
, 2012 Global commitments aim to provide antiretroviral therapy (ART) to 15 million people living with HIV by 2015, and recent studies have demonstrated the potential for widespread ART to prevent HIV transmission.
Andrieux-Meyer, Isabelle +10 more
core +4 more sources
Pharmacological incompatibility
Бюллетень сибирской медицины, 2003 In the lecture there have been studied pharmacokinetic and pharmacodynamic mechanisms of drug undesirable interaction at combined pharmacotherapy and have been cited the urgent for general practitioner examples of pharmacological incompatibility.
A. I. Vengerovsky
doaj +1 more source
Application of hot melt extrusion for improving bioavailability of artemisinin a thermolabile drug [PDF]
, 2017 Hot melt extrusion has been used to produce a solid dispersion of the thermolabile drug artemisinin. Formulation and process conditions were optimized prior to evaluation of dissolution and biopharmaceutical performance.
A. L. Kelly +8 more
core +2 more sources
Drug incompatibility in the ICU: review of implications in nursing practice
Revista Eletrônica de Enfermagem, 2017 This is an integrative review of the literature performed in seven databases, with the aim of analyzing the scientific production on potential drug incompatibilities in ICUs, and mapping the most prevalent incompatible drugs described in the literature ...
Graciele Oroski Paes +3 more
doaj +1 more source
Genome Sequence of the Chestnut Blight Fungus Cryphonectria parasitica EP155: A Fundamental Resource for an Archetypical Invasive Plant Pathogen. [PDF]
, 2020 Cryphonectria parasitica is the causal agent of chestnut blight, a fungal disease that almost entirely eliminated mature American chestnut from North America over a 50-year period. Here, we formally report the genome of C. parasitica EP155 using a Sanger
Aerts, Andrea +14 more
core
, 2006 Electrostatics plays a key role in biomolecular assembly. Oppositely charged biomolecules, for instance, can co-assembled into functional units, such as DNA and histone proteins into nucleosomes and actin-binding protein complexes into cytoskeleton ...
Barrat J. L. +5 more
core +1 more source
Pattern formation on the surface of cationic-anionic cylindrical aggregates
, 2005 Charged pattern formation on the surfaces of self--assembled cylindrical micelles formed from oppositely charged heterogeneous molecules such as cationic and anionic peptide amphiphiles is investigated.
A. Ben-Naim +7 more
core +1 more source