Results 61 to 70 of about 61,983 (302)

Thermal and Isothermal Methods in Development of Sustained Release Dosage Forms of Ketorolac Tromethamine

E-Journal of Chemistry, 2008
Differential scanning calorimetry (DSC) is a rapid and convenient and conclusive method of screening drug-polymer blend during preformulation studies as it allows polymer incompatibility to be established instantaneously.
Dimple Chopra, Vivek Ranjan Sinha, Manjeet Singh   +2 more
doaj   +1 more source

The Inflation Technique for Causal Inference with Latent Variables

, 2019
The problem of causal inference is to determine if a given probability distribution on observed variables is compatible with some causal structure. The difficult case is when the causal structure includes latent variables.
Fritz, Tobias, Spekkens, Robert W., Wolfe, Elie   +2 more
core   +1 more source

Psycho-physiologic emergentism; four minds in a body [PDF]

, 2017
The mind-body problem represents one of the most debated topics in the neurosciences. From a psychological standpoint, abstract/non-material data are an intrinsic part of the mind, intervening to a large extent in reasoning and decision making processes.
Motofei, Ion G., Rowland, David L.
core   +3 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Interação medicamentosa no serviço de emergência

Einstein (São Paulo)
OBJETIVO: Identificar a ocorrência de potenciais interações medicamentosas em prescrições médicas de pacientes adultos internados no Serviço de Emergência do Hospital São Paulo. MÉTODOS: Estudo de corte transversal e descritivo.
Meiry Fernanda Pinto Okuno, Raíssa Silveira Cintra, Cássia Regina Vancini-Campanharo, Ruth Ester Assayag Batista   +3 more
doaj   +1 more source

Joint perception: gaze and social context [PDF]

, 2012
We found that the way people looked at images was influenced by their belief that others were looking too. If participants believed that an unseen other person was also looking at what they could see, it shifted the balance of their gaze between negative
Ghane Cavanaugh, A., Hoover, M.A., Kirkham, Natasha Z., Richardson, D.C., Street, C.N.H., Tan, J.Y.M.   +5 more
core   +2 more sources

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

The effect of family-oriented neuropsychological training interventions on marital incompatibilities and cognitive-emotional regulation of married clients addicted to drugs [PDF]

مجله علوم روانشناختی
Background: One of the common problems in the families of drug addicts is marital incompatibility and cognitive-emotional regulation. One of the effective treatments for marital incompatibility and cognitive-emotional regulation is family-oriented ...
Hanieh Goli Rostami, Saeed Pournagash Motlaq Tehrani, Fereydoun Yariari, Gholamali Afrooz   +3 more
doaj  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source