Results 141 to 150 of about 7,614,121 (392)
The drug industry: the goose that lays the golden drugs. [PDF]
, 1980 Trisha Smith
openalex +1 more source
A Profile of the Philippine Pharmaceutical Sector [PDF]
, 2011 The Philippines is one of the biggest pharmaceutical markets in the ASEAN region, next only to Indonesia and Thailand. It is a lifeline to thousands of Filipino workers and a significant contributor in terms of value of output.
Asis, Ronina D. +4 more
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Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
The Value of Failures in Pharmaceutical R&D [PDF]
, 2012 We build a cumulative innovation model in which both success and failure provide valuable information for future research. To test this learning mechanism, we use a dataset covering outcomes of world-wide R&D projects in the pharmaceutical industry, and ...
Chiou, Jing-Yuan +3 more
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Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
O mercado privado de vacinas no Brasil: a mercantilização no espaço da prevenção
Cadernos de Saúde PúblicaEste artigo tem como objetivo principal a análise do mercado de vacinas no Brasil, que está caracterizado como composto de dois segmentos com práticas e lógicas distintas: o segmento público voltado para a oferta ao interior do Sistema Único de Saúde ...
José Gomes Temporão
doaj
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Biotechnology and the pharmaceutical industry. New cardiovascular drugs. [PDF]
, 1986 Mark D. Dibner, P B Timmermans
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Reconciling social and industrial goals: a bargaining model to pricing pharmaceuticals [PDF]
The issues at stake for determining the price of a drug are related to finding an "equitable" trade-off between the legitimate need for the pharmaceutical industry to make a profit and full exploitation of the consumer’s surplus in a market with ...
Rosella Levaggi, Stefano Capri
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Why do Particle Clouds Generate Electric Charges?
, 2015 Grains in desert sandstorms spontaneously generate strong electrical charges; likewise volcanic dust plumes produce spectacular lightning displays. Charged particle clouds also cause devastating explosions in food, drug and coal processing industries ...
AA Mills +31 more
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