Results 61 to 70 of about 5,201,027 (314)
Disposal Management in Biological-Pharmaceutical Centers of Alborz Province, Iran
تحقیقات نظام سلامت, 2021 Background: Wastewater is highly sensitive in pharmaceutical industries due to its various microbial and chemical pollutions, and its proper management is of special importance.
Hassan Mardani
doaj
BMC Cancer, 2020 Background Hepatocellular carcinoma (HCC) is a common malignant tumor with characteristics of poor prognosis, high morbidity and mortality worldwide.
Di Ma +4 more
doaj +1 more source
Drug nanocrystals - versatile option for formulation of poorly soluble materials [PDF]
, 2018 Poor solubility of drug compounds is a great issue in drug industry today and decreasing particle size is one efficient and simple way to overcome this challenge.
Peltonen, Leena +3 more
core +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Finnish Journal of eHealth and eWelfareThe study investigates how pharmaceutical companies currently utilize, and how they could further utilize, prescription and dispensation data from the centralized outpatient medication data sources Kelasto and Kanta services for research, pricing ...
Johanna Palvimo +3 more
doaj +1 more source
Brief strategic family therapy for adolescent drug abuse. [PDF]
, 2003 To ensure that treatment providers apply the most current scientifically supported approaches to their patients, NIDA has supported the development of the "Therapy Manuals for Drug Addiction" series.
core
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Regulating the drugs industry transparently [PDF]
BMJ, 2005 Over the past 10-15 years, drug regulatory authorities in the United Kingdom and elsewhere have streamlined and accelerated the review of new drugs in response to claims by the pharmaceutical industry that over-regulation was stifling innovation.1,2 Despite these policies, the number of new molecular entities—a standard measure of innovation in the ...
openaire +3 more sources
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source