Drug information sources in professional work-a questionnaire study on physicians' usage and preferences (the drug information study). [PDF]
Eur J Clin Pharmacol, 2023 Seidel P +6 more
europepmc +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
A (des)informação sobre medicamentos: o duplo padrão de conduta das empresas farmacêuticas
Cadernos de Saúde PúblicaDiferentes fatores foram identificados como exercendo influência sobre o comportamento dos prescritores de medicamentos. Estudos realizados enfatizam o lugar proeminente ocupado pelas fontes de informação disponíveis para os médicos, muitos deles ...
José Augusto C. Barros
doaj
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Cadernos de Saúde PúblicaO texto apresenta uma visão crítica da interação entre prescritores, dispensadores e pacientes, vislumbrando, na informação, um dos fatores-chave para o desenvolvimento qualitativo dessa complexa relação. Descreve, além do aporte de informações por parte
Vera Lúcia Edais Pepe +1 more
doaj
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Exploring the training of chinese medical staff oriented to the need for clinical drug information services: from the perspective of drug information patients obtained and need. [PDF]
BMC Med Educ, 2023 Huang R, Huang Y, Liu J, Chen L.
europepmc +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
PEMBERDAYAAN HAK KONSUMEN ATAS INFORMASI OBAT
Jurnal Media Hukum, 2014 This research aims to investigate and identify the empowerment of consumer rights on drug information. Research questions focused on how the role of the Food and Drug Supervisory Agency (BPOM) and pharmacists in the empowering consumers on drug ...
Norma Sari
doaj