Results 121 to 130 of about 2,100,146 (305)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Performance and risks of ChatGPT used in drug information: comment. [PDF]

Eur J Hosp Pharm, 2023
Kleebayoon A, Wiwanitkit V.
europepmc   +1 more source

UMD Drug Educ and Info Center (1977-06-15)

, 1977
University of Minnesota, Duluth. Center for Drug Education and Information. (1977). UMD Drug Educ and Info Center (1977-06-15).
University of Minnesota, Duluth. Center for Drug Education and Information
core  

Policing alcohol and illicit drug use among Aboriginal and Torres Strait Islander people in metropolitan environments [PDF]

, 2014
Executive summary: This report presents the results of Australian Institute of Criminology research on issues and challenges of policing alcohol and illicit drug use among Aboriginal and Torres Strait Islander people in metropolitan environments.
David Marks, Jason Payne, Tracy Cussen
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Drug information sources in professional work-a questionnaire study on physicians' usage and preferences (the drug information study). [PDF]

Eur J Clin Pharmacol, 2023
Seidel P, Rolander B, Eriksson AL, Lindahl U, Wallerstedt SM, Hägg S, Kling A.   +6 more
europepmc   +1 more source

UMD Drug Educ and Info Center (1977-04-15)

, 1977
University of Minnesota, Duluth. Center for Drug Education and Information. (1977). UMD Drug Educ and Info Center (1977-04-15).
University of Minnesota, Duluth. Center for Drug Education and Information
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

UMD Drug Educ and Info Center (1976-11-15)

, 1976
University of Minnesota, Duluth. Center for Drug Education and Information. (1976). UMD Drug Educ and Info Center (1976-11-15).
University of Minnesota, Duluth. Center for Drug Education and Information
core  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source