Results 61 to 70 of about 2,100,146 (305)

Establishment and application of China's first pediatric rational medication intelligent decision system database

open access: yesFrontiers in Pediatrics
ObjectiveThe incidence of medication errors is much higher among children because of their unique characteristics. This study aims to establish the first Pediatric Rational Medication Intelligent Decision System (PRMIDS) database in China and apply it to
Dan Wu   +10 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Other title: Appropriate Drug Utilization

open access: yes, 2010
application/pdf; "Program Outcomes: Evaluating, Measuring, and Identifying Patient Care Benefits and Cost Reduction."; Dates listed represent dates the individual reports were "mailed." All reports were prepared in March 2012 and ...
Health Information Designs.
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Behavioral changes after the SHS-awareness campaign conducted in Ukraine in 2019

open access: yesTobacco Prevention and Cessation, 2020
Background The secondhand smoke (SHS) awareness campaign held in Ukraine in summer 2019 aimed to raise awareness regarding the dangers of SHS exposure and to encourage activities able to diminish smoking in smoke-free zones.
Tatiana Andreeva   +3 more
doaj   +1 more source

Salt Lake City, Utah Profile of Drug Indicators

open access: yes, 1999
The following profile contains information on demographics, political figures, funding, programs, crime, drug use, drug trafficking, and enforcement ...
Office of National Drug Control Policy   +1 more
core  

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

A Comparative Study of Drug Package Inserts of High Selling Cardiac Drugs against the Drug Regulations of Iranian Food and Drug Administration [PDF]

open access: yesTaṣvīr-i salāmat, 2019
Background and Objectives: The Drug Package Insert (PI) is a written information provided by drug manufacturers to deliver essential information for the consumer.
Sedigheh Mirzadeh Qasabeh   +1 more
doaj  

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