Results 181 to 190 of about 11,447,845 (407)

Drug interaction (24. drug-drug interactions in intensive care unit) [PDF]

open access: yes, 2012
Konuma, Toshimitsu   +3 more
core   +1 more source

Analisis Potensi Interaksi Obat Antidiabetik Oral Pada Pasien Di Instalasi Rawat Jalan Askes Rumah Sakit Dokter Soedarso Pontianak Periode Januari- Maret 2013 [PDF]

open access: yes, 2013
Drug interaction is one of eight drug-related problems categories that may affectpatient clinical outcome. Increasing complexity of the drugs used in current treatment andthe likelihood of polypharmacy practices, make possible the incident of drug ...
Utami, M. G. (Mega)
core  

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Rhabdomyolysis secondary to drug interaction between atorvastatin, omeprazole, and dexamethasone

open access: yesInternational Medical Case Reports Journal, 2012
Shereen Elazzazy,1 Saad S Eziada,2 Manal Zaidan11Pharmacy Department, 2Oncology Hematology Department, National Center for Cancer Care and Research, Hamad Medical Corporation, Doha, QatarAbstract: Concomitant administration of atorvastatin, omeprazole ...
Elazzazy S, Eziada SS, Zaidan M
doaj  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Kernel methods for in silico chemogenomics

open access: yes, 2007
Predicting interactions between small molecules and proteins is a crucial ingredient of the drug discovery process. In particular, accurate predictive models are increasingly used to preselect potential lead compounds from large molecule databases, or to
Jacob, Laurent, Vert, Jean-Philippe
core   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

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