Results 231 to 240 of about 1,087,510 (314)

Drug Interaction Potential of Berberine Hydrochloride When Co-Administered with Tofacitinib and Filgotinib in Rats. [PDF]

Drug Des Devel Ther
Wang J, Lu S, Zhang C, Wang J, Wu H, Li G.   +5 more
europepmc   +1 more source

Mitochondria‐associated membranes (MAMs): molecular organization, cellular functions, and their role in health and disease

FEBS Open Bio, EarlyView.
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui, Maryline Santerre, Natalia Shcherbik, Bassel E Sawaya   +3 more
wiley   +1 more source

Medication Extraction and Drug Interaction Chatbot: Generative Pretrained Transformer-Powered Chatbot for Drug-Drug Interaction. [PDF]

Mayo Clin Proc Digit Health
Kim WT, Shin J, Yoo IS, Lee JW, Jeon HJ, Yoo HS, Kim Y, Jo JM, Hwang S, Lee WJ, Park S, Kim YJ.   +11 more
europepmc   +1 more source

Visualization of drug-nucleic acid interactions at atomic resolution. IV. Structure of an aminoacridine/dinucleoside monophosphate crystalline complex, 9-aminoacridine: 5-iodocytidylyl(3'-5')guanosine

, 1979
T. D. Sakore, B. Subba Reddy, Henry M. Sobell   +2 more
openalex   +2 more sources

Interplay between RNA‐protein interactions and RNA structures in gene regulation

FEBS Open Bio, EarlyView.
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko, Mauro Scaravilli, Minna‐Liisa Änkö   +2 more
wiley   +1 more source

MFE-DDI: A multi-view feature encoding framework for drug-drug interaction prediction. [PDF]

Comput Struct Biotechnol J
Wang L, Li Y, Zhou Y, Guo L, Chen C.
europepmc   +1 more source

Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium

FEBS Open Bio, EarlyView.
By selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Tomoaki R. Yamashita, Toyonobu Usuki, Robert R. Kay, Tamao Saito   +3 more
wiley   +1 more source

A Drug-Drug Interaction Study Evaluating the Pharmacokinetic Consequences of Obicetrapib Therapy on Atorvastatin or Rosuvastatin Levels in Healthy Volunteers. [PDF]

Am J Cardiovasc Drugs
Kastelein JJP, Ditmarsch M, Hsieh A, Kling D, Walker A, Dicklin MR, Tayab Z, Bouhajib M, Davidson MH.   +8 more
europepmc   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Drug-drug interaction prediction of traditional Chinese medicine based on graph attention networks. [PDF]

Sci Rep
Yang B, Song D, Li Y, Wang J.
europepmc   +1 more source