Results 251 to 260 of about 1,220,078 (316)

Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird, Haley McQuown, Jihyun Park, Samuel J. Teener, Ian F. Webber‐Davis, Andrew D. Carter, Dae‐Gyu Jang, Eva L. Feldman, Stephen A. Goutman, Benjamin J. Murdock   +9 more
wiley   +1 more source

Assessment of Pharmacokinetic Drug Interaction of Asciminib with Atorvastatin in Healthy Participants. [PDF]

Clin Pharmacol Drug Dev
Hoch M, Weis W, Huth F, Jamalapuram S, Quinlan M, Bandaru A, Bellibas SE, Mirkou A, Kapoor S, Kakar S.   +9 more
europepmc   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source

Associations between antihypertensive drug-related gene polymorphisms and cardiovascular outcomes in hypertensive patients: a gene-drug interaction study. [PDF]

Sci Rep
Li Z, Liu H, Chen M, Deng J, Ma Z, Huang G, Li C, Su M, Zhong H.   +8 more
europepmc   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Contrastive learning-based multi-mechanism disentangled assessment for drug-drug interaction. [PDF]

BMC Bioinformatics
Zhang J, Zeng Y, Tang C, Zhong C, Wen H, Liu Y.   +5 more
europepmc   +1 more source

UGT2B7-mediated drug-drug interaction between cannabinoids and hydromorphone. [PDF]

Drug Metab Dispos
Coates S, Bardhi K, Zhao M, Lazarus P.
europepmc   +1 more source

<i>In silico</i> and <i>in vitro</i> investigations of the drug-drug interaction mechanisms between fludarabine and busulfan. [PDF]

Front Pharmacol
Ben Hassine K, Robin S, Baleydier F, Mseddi M, Mlakar V, Muthukumaran J, Ansari M, Satyanarayana Uppugunduri CR.   +7 more
europepmc   +1 more source

A Dose-Aware Model for Revealing Dose-Risk Relationship of Drug-Drug Interaction. [PDF]

CPT Pharmacometrics Syst Pharmacol
Shi Y, Sun A, Yang Y, Nan H, Xu J, Shan M, Eadon MT, Su J, Zhang P.   +8 more
europepmc   +1 more source

Drug-Drug Interaction Management Among Pharmacists in Jordan: A National Comparative Survey. [PDF]

Pharmacy (Basel)
Abdel-Qader DH, Al-Kubaisi KA, Taybeh E, Al Mazrouei N, Ibrahim R, Albassam A.   +5 more
europepmc   +1 more source