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Optimized UPLC-MS/MS Method for the Simultaneous Quantification of Pazopanib and GSK-1268997 and Its Application to Drug-Drug Interaction Studies. [PDF]
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Gerontologia Clinica, 2009
Drugs for allergy are often taken in combination with other drugs, either to treat allergy or other conditions. In common with many pharmaceuticals, most such drugs are subject to metabolism by P450 enzymes and to transmembrane transport. This gives rise to considerable potential for drug-drug interactions, to which must be added consideration of drug ...
Alan, Boobis +5 more
openaire +4 more sources
Drugs for allergy are often taken in combination with other drugs, either to treat allergy or other conditions. In common with many pharmaceuticals, most such drugs are subject to metabolism by P450 enzymes and to transmembrane transport. This gives rise to considerable potential for drug-drug interactions, to which must be added consideration of drug ...
Alan, Boobis +5 more
openaire +4 more sources
Current Opinion in Anaesthesiology, 2001
The prevalence of undesirable drug interactions is substantial but largely unknown. Although drug interactions are certainly an important cause of drug toxicity, their clinical significance may have been exaggerated. This review presents a brief overview of possible drug interactions.
K T, Olkkola, J, Ahonen
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The prevalence of undesirable drug interactions is substantial but largely unknown. Although drug interactions are certainly an important cause of drug toxicity, their clinical significance may have been exaggerated. This review presents a brief overview of possible drug interactions.
K T, Olkkola, J, Ahonen
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Clinics in Podiatric Medicine and Surgery, 1992
Drug-drug interactions are most likely to occur in patients receiving multiple medications and with drugs that have a narrow therapeutic window. The outcome may be harmful or beneficial, but the relative incidence of clinically important adverse drug interactions remains unknown.
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Drug-drug interactions are most likely to occur in patients receiving multiple medications and with drugs that have a narrow therapeutic window. The outcome may be harmful or beneficial, but the relative incidence of clinically important adverse drug interactions remains unknown.
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Veterinary Clinics of North America: Small Animal Practice, 1988
Drug interactions are often the result of complex biochemical, physical, and kinetic factors and may not often be easily predicted or even recognized. Although this article has attempted to point out the more common mechanisms and results of drug interactions, the few interactions that have been documented in small animals are undoubtedly only the tip ...
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Drug interactions are often the result of complex biochemical, physical, and kinetic factors and may not often be easily predicted or even recognized. Although this article has attempted to point out the more common mechanisms and results of drug interactions, the few interactions that have been documented in small animals are undoubtedly only the tip ...
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Drug–drug interaction with statins
Expert Review of Clinical Pharmacology, 20083-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase inhibitors (the so-called statins: atorvastatin, fluvastatin, pravastatin, lovastatin, rosuvastatin and simvastatin) are a well-established class of drugs in the treatment of hypercholesterolemia. Statin monotherapy is generally well tolerated, with a low frequency of adverse events.
A. Corsini, S. Bellosta
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Drug—Drug Interactions in the Elderly
Annals of Pharmacotherapy, 2002OBJECTIVE: To detect the frequency of potential drug—drug interactions (DDIs) in an outpatient group of elderly people in 6 European countries, as well as to describe differences among countries. DATA SOURCES AND METHODS: Drug use data
Ingeborg K Björkman +23 more
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Drug Interactions with Antiviral Drugs
Clinical Pharmacokinetics, 1996Antiviral drug interactions are a particular problem among immuno-compromised patients because these patients are often receiving multiple different drugs, i.e. antiretroviral drugs and drugs effective against herpesvirus. The combination of zidovudine and other antiretroviral drugs with different adverse event profiles, such as didanosine, zalcitabine
A M, Taburet, E, Singlas
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