Results 281 to 290 of about 11,447,845 (407)

Association Study of OATP1B3 Polymorphisms on Hepatic Uptake and Drug-Drug Interaction <i>In Vitro</i>. [PDF]

ACS Omega
Yang Z, Chen Y, Tian G, Wang X, Wang Z.
europepmc   +1 more source

A physiologically-based pharmacokinetic precision dosing approach to manage dasatinib drug-drug interactions

Schwab, Matthias
openalex   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

FEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata, Yoshikazu Saito, Yoichi Kasahara, Wataru Fujii, Takumi Misaka, Tomiko Asakura, Masataka Narukawa   +6 more
wiley   +1 more source

An Evaluation of the Drug Interaction Potential of Encorafenib in Combination With Binimetinib Using the Inje Cocktail in Patients With Cancer. [PDF]

Clin Pharmacol Ther
Piscitelli J, Reddy MB, Wollenberg L, Del Frari L, Gong J, Matschke K, Williams JH.   +6 more
europepmc   +1 more source

Docking aggregates and elaborate interaction of Afimetoran drug with wild and nsSNPs (R28Q, T40M, P59L, R200C), containing key residues, distances, angles and binding energies.

Obaid Habib (22615046), Saqib Ishaq (22615049), Kamran Habib (22615052), Aishma Khattak (11261634), Wei Yang (109917), Zesong Li (151039), Kainat Bukhari (22615055), Amin Ullah (12015113), Ajaz Ahmad (1408756), Qurban Ali (3700123)   +9 more
openalex   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Vascularized Tumor-on-a-Chip Model as a Platform for Studying Tumor-Microenvironment-Drug Interaction. [PDF]

Macromol Biosci
Kim H, Cho SW, Kim HN.
europepmc   +1 more source

Antiepileptic Drug Interactions in Polytherapy Patients

J. S. Venkatesh*, Dr. Santosh Uttangi, Aleena R Reji, Aneeta G Jacob, Bhoomika K S, Dona Aju
openalex   +1 more source

Drug Interactions in the Bovine Animal

, 1976
J. W. Paul
openalex   +2 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source