Results 111 to 120 of about 1,909,397 (348)
Background: Clinically significant drug-drug interactions can be defined as events in which the pharmacodynamics or pharmacokinetic characteristics of a drug are modified by coadministration of a second drug to the patient’s medication protocol, which ...
Raz Muhammed HamaSalih+4 more
doaj +1 more source
PHARMACOGENETICS AND INTERACTIONS OF ANTIDEPRESSANTS IN THE TREATMENT OF CO-MORBID ILLNESS [PDF]
Patients who require long-term treatment for depression have an increased risk of experiencing drug interactions since they will take medications for and/or co-morbid illness. Antidepressants can be the object of drug interactions by other substances, or
Alma Mihaljević-Peleš+4 more
core +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo+18 more
wiley +1 more source
Yelbeneh Abayneh Assefa,1 Ansha Kedir,1 Wubayehu Kahaliw2 1Department of Pharmacology and Clinical Pharmacy, School of Pharmacy, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia; 2Department of Pharmacology, School of Pharmacy ...
Assefa YA, Kedir A, Kahaliw W
doaj
Psychotropic Drugs (2) Interaction between Monoamine Oxidase (MAO) Inhibitors and other Substances [PDF]
Folke Sjöqvist
openalex +1 more source
Era of direct acting anti-viral agents for the treatment of hepatitis C. [PDF]
Hepatitis C infection is universal and the most common indication of liver transplantation in the United States. The period of less effective interferon therapy with intolerable side effects has gone.
Ahmed, Monjur
core +1 more source
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song+11 more
wiley +1 more source
The Interaction of Anesthetic Agents and Adrenergic Drugs to Produce Cardiac Arrhythmias [PDF]
Ronald L. Katz, Ralph Epstein
openalex +1 more source
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton+17 more
wiley +1 more source
THE INTERACTION OF SOME STIMULANT AND DEPRESSANT DRUGS ON THE FROG HEART [PDF]
J. L. BROADBENT
openalex +1 more source