Results 191 to 200 of about 1,977,520 (346)

Indoleamine 2,3‐dioxygenase 1 inhibition reverses cancer‐associated fibroblast‐mediated immunosuppression in high‐grade serous ovarian cancer

FEBS Open Bio, EarlyView.
CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee, Jung Yoon Ho, In Sun Hwang, Youn Jin Choi   +3 more
wiley   +1 more source

Pharmacological Interaction between Galphimine-A, a Natural Anxiolytic Compound and Gabaergic Drugs [PDF]

, 2015
Dante Avilés-Montes, Maribel Herrera- Ruiz, Ruben Roman- Ramos, Enrique Jiménez‐Ferrer, Manasés González‐Cortazar, Alejandro Zamilpa, Jaime Tortoriell   +6 more
openalex   +1 more source

Antiretroviral therapy and associated drug interactions with cardiovascular drugs: a critical review. [PDF]

Front Pharmacol
Spanakis M, Alexakis K, Ioannou P.
europepmc   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Antiparkinsonian drugs, mental disorders in patients with Parkinson's disease and drug‑drug interactions [PDF]

, 2018
Michal Prokeš, Josef Suchopár
openalex   +1 more source

Knowledge, attitudes, and practices toward linezolid-serotonergic drug interactions: a cross-sectional study. [PDF]

Front Pharmacol
Aldairem A, Almohareb SN, Alowais SA, Shawaqfeh MS, Alzahrani AA, Alzahrani AY, Alqahtani KH, Bin Saleh K.   +7 more
europepmc   +1 more source

Drug Interaction

New England Journal of Medicine, 1970
openaire   +4 more sources

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Pharmacist Intervention Models in Drug–Drug Interaction Management in Prescribed Pharmacotherapy [PDF]

Ivana Samardžić, Ivana Marinović, Iva Marović, Nikolina Kuča, Vesna Bačić Vrca, Ivana Samardžić, Ivana Marinović, Iva Marović, Nikolina Kuča, Vesna Bačić Vrca   +9 more
openalex   +1 more source

Assessment of Potential Drug–Drug Interactions and Their Predictors in Chronic Outpatient Department of Dessie Referral Hospital, Dessie, Northeast Ethiopia

, 2021
Mengistie Yirsaw Gobezie, Hailu Birhanu Bitew, Abdu Tuha, Haftom Gebregergs Hailu   +3 more
openalex   +2 more sources