Results 171 to 180 of about 1,107,910 (309)

Role of metabolites in drug-drug interactions. [PDF]

Drug Metab Pharmacokinet
Isoherranen N.
europepmc   +1 more source

Drug Interactions [PDF]

Anaesthesia and Intensive Care, 1975
openaire   +2 more sources

Prediction of the Pharmacokinetic Drug Interactions of Direct Oral Anticoagulants Using Mechanistic Static Modelling [PDF]

Background Direct oral anticoagulants are cardiovascular drugs used in the clinical treatment and prevention of thromboembolism. Pharmacokinetic drug interactions may cause a decrease or several-fold increases in their exposure leading to unfavourable ...
Schaat, Mostafa
core  

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Food-drug interactions knowledge and clinical competence among registered dietitians. [PDF]

BMC Med Educ
Beirão S, Rossoni C, Ferreira-Pêgo C, Costa JG.   +3 more
europepmc   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Nationwide assessment of community pharmacists' practices and atorvastatin-drug interactions in Egypt. [PDF]

Sci Rep
Maslub MG, Radwan MA, Daud NAA, Abd-Alla ZA, El-Mohamdy MA.   +4 more
europepmc   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Pharmacomicrobiomics in Psoriasis: Microbiome-Drug Interactions Across Systemic Treatments. [PDF]

Life (Basel)
Santaniello U, Mastorino L, Pala V, Rosset F, Crespi O, Quaglino P, Ribero S.   +6 more
europepmc   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, EarlyView.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source