Results 101 to 110 of about 244,106 (290)
Drug addiction in the labeling theory [PDF]
, 2013 Drug addiction phenomenon in the modern society takes on alarming proportions. Despite extensive prevention programs in Western European society, it is estimated that more than half of adolescents smoke marijuana (Aldridge, 2008, pp. 189-206).
Szwejka, Łukasz
core
Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis [PDF]
, 2003 Superparamagnetic iron oxide nanoparticles have been used for many years as magnetic resonance imaging contrast agents or in drug delivery applications.
Berry, C.C. +3 more
core +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Classifying Free Texts Into Predefined Sections Using AI in Regulatory Documents: A Case Study with Drug Labeling Documents. [PDF]
Chem Res Toxicol, 2023 Gray M, Xu J, Tong W, Wu L.
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Mining FDA drug labels using an unsupervised learning technique - topic modeling
BMC Bioinformatics, 2011 Background The Food and Drug Administration (FDA) approved drug labels contain a broad array of information, ranging from adverse drug reactions (ADRs) to drug efficacy, risk-benefit consideration, and more.
Xu Xiaowei +4 more
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
The Decline in Consumer Use of Food Nutrition Labels, 1995-2006 [PDF]
This report examines changes in consumers’ use of nutrition labels on food packages between 1995-96 and 2005-06. The analysis finds that, although a majority of consumers report using nutrition labels when buying food, use has declined for most label ...
Variyam, Jayachandran N. +1 more
core +1 more source
"In vitro" and "in vivo" drug targeting using biotinylated immunoliposomes [PDF]
, 2005 The aim of my thesis was the optimization, characterization and application of a new, innovative drug carrier system which can be used to target pharmaceuticals to diseased tissues and organs.
Schnyder, Anita
core +1 more source
Drug labeling changes and pediatric hematology/oncology prescribing: Measuring the impact of U.S. legislation. [PDF]
Clin Trials, 2021 Benning TJ +5 more
europepmc +1 more source