Results 121 to 130 of about 243,161 (291)
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
TOWARD A MORE COMPREHENSIVE THEORY OF FOOD LABELING
Agribusiness, Food Consumption/Nutrition/Food Safety,
Padberg, Daniel I., Caswell, Julie A.
core
Affinity‐Directed Site‐Specific Protein Labeling and Its Application to Antibody‐Drug Conjugates
Advanced ScienceChemically modified proteins have diverse applications; however, conventional chemo‐selective methods often yield heterogeneously labeled products. To address this limitation, site‐specific protein labeling holds significant potential, driving extensive ...
Sooin Kim +9 more
doaj +1 more source
GenAI-Powered Framework for Reliable Sentiment Labeling in Drug Safety Monitoring
Applied SciencesThe analysis of medical data presents an opportunity for healthcare systems to support decision-making and improve patient outcomes. In this context, the automated analysis of user-generated drug reviews offers a promising approach for monitoring ...
Eleftherios Vouzis, Ilias Maglogiannis
doaj +1 more source
Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett +8 more
wiley +1 more source
IDENTITY PRESERVATION AND FALSE NON-GMO LABELING IN THE FOOD SUPPLY CHAIN
This paper addresses two issues pertaining to the market differentiation between non-genetically modified and genetically modified food varieties. First, a cost-efficiency explanation of the discrepancy between the observed shares of identity preserved ...
Saak, Alexander E.
core
Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall +16 more
wiley +1 more source
Drug addiction in the labeling theory
, 2013 Drug addiction phenomenon in the modern society takes on alarming proportions. Despite extensive prevention programs in Western European society, it is estimated that more than half of adolescents smoke marijuana (Aldridge, 2008, pp. 189-206).
Szwejka, Łukasz
core
Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina +11 more
wiley +1 more source