Results 81 to 90 of about 2,201,898 (294)
SOME ECONOMIC IMPLICATIONS OF PUBLIC LABELING [PDF]
This article discusses economic issues related to public labeling. The main contributions in both the empirical and theoretical literatures are presented in order to motivate responses to the questions, when should a regulator promote public labeling ...
Marette, Stephan, Crespi, John M.
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Super Fibonacci Graceful Labeling of Some Special Class of Graphs [PDF]
, 2011 A Fibonacci graceful labeling and a super Fibonacci graceful labeling on graphs were introduced by Kathiresan and Amutha in ...
Sridevi, R. +2 more
core +1 more source
Label-free drug discovery [PDF]
Frontiers in Pharmacology, 2014 Current drug discovery is dominated by label-dependent molecular approaches, which screen drugs in the context of a predefined and target-based hypothesis in vitro. Given that target-based discovery has not transformed the industry, phenotypic screen that identifies drugs based on a specific phenotype of cells, tissues, or animals has gained renewed ...
openaire +3 more sources
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Syntax-driven argument identification and multi-argument classification for semantic role labeling [PDF]
, 2007 Semantic role labeling is an important stage in systems for Natural Language Understanding. The basic problem is one of identifying who did what to whom for each predicate in a sentence. Thus labeling is a two-step process: identify constituent phrases
Lin, Chi-San Althon
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Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Consumer perceptions of front-of-package traffic-light food labeling [PDF]
, 2009 Includes bibliographical ...
Bronner, Kara
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Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
Is the Food and Drug Administration Safe and Effective? [PDF]
In the United States, drug safety and efficacy are primarily regulated by the Food and Drug Administration (FDA) and the legal system, which gives manufacturers large incentives to produce safe drugs and provide proper warnings for side effects, since ...
Eric Sun, Tomas J. Philipson
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