Results 21 to 30 of about 244,106 (290)

Do asian patients require only half of the clozapine dose prescribed for caucasians? A critical overview

Indian Journal of Psychological Medicine, 2020
Since 1997, studies have found that Asians need lower clozapine doses than Caucasians. Caucasians with average clozapine metabolism may need from 300 to 600 mg/day to reach the therapeutic range (350 ng/ml). Thus, serum clozapine concentration-to-dose (C/
Jose de Leon, Anto P Rajkumar, Arun R Kaithi, Georgios Schoretsanitis, John M Kane, Chuan-Yue Wang, Yi-Lang Tang, Shih-Ku Lin, Kyung Sue Hong, Saeed Farooq, Chee H Ng, Can-Jun Ruan, Chittaranjan Andrade   +12 more
doaj   +1 more source

Real-World Amount of Clotting Factor Concentrates Dispensed and Annual Medical Expenditures for Japanese Patients with Hemophilia B

Journal of Blood Medicine, 2023
Katsuyuki Fukutake,1,2 Kanae Togo,3 Linghua Xu,3 Leona E Markson,4 José Maria Jimenez Alvir,5 Ian Winburn,6 Toshiyuki Karumori3 1Laboratory Medicine, Tokyo Medical University, Shinjuku, Tokyo, Japan; 2Department of Blood Coagulation Diseases, Ogikubo ...
Fukutake K, Togo K, Xu L, Markson LE, Alvir JMJ, Winburn I, Karumori T   +6 more
doaj  

Cardiovascular Drug Labeling: Do They Have Information on Necessary Precautions for Older People? [PDF]

Geriatrics, Gerontology and Aging
OBJECTIVE: To analyze the existence of information on drug labeling intended for health professionals on the precaution of cardiovascular drugs use in older people.
Lucas Oliveira Marques, Roberta Coutinho Vasconcelos, André Oliveira Baldoni, Ana Cristina Nogueira Rodrigues Pestana, Farah Maria Drumond Chequer   +4 more
doaj   +1 more source

Clinical pharmacology information in regulatory submissions and labeling: A comparative analysis of orphan and non‐orphan drugs approved by the FDA

Clinical and Translational Science, 2022
Clinical pharmacology is an integral discipline supporting the development, regulatory evaluation, and clinical use of drugs for the treatment of both common and rare diseases.
Julie Hsieh, Martina Sahre, Xinning Yang, Rajanikanth Madabushi, Anuradha Ramamoorthy   +4 more
doaj   +1 more source

Visible-Light-Driven Reduction of CO2 to CO and Its Subsequent Valorization in Carbonylation Chemistry and C-13 Isotope Labeling [PDF]

, 2018
WOS:000441548500003International audienceA convenient and safe approach in valorizing carbon monoxide (CO) produced from the photocatalytic reduction of carbon dioxide (CO2) has been investigated.
Vecchio, Antonio, Gotico, Philipp, Halime, Zakaria, Leibl, Winfried, Antonio Del Vecchio, Philipp Gotico, Winfried Leibl, Zakaria Halime, Annamaria Quaranta, Davide Audisio, Del Vecchio, Antonio, Quaranta, Annamaria, Ally Aukauloo, Aukauloo, Ally, Audisio, Davide   +14 more
core   +1 more source

A Comparative Study of Drug Package Inserts of High Selling Cardiac Drugs against the Drug Regulations of Iranian Food and Drug Administration [PDF]

Taṣvīr-i salāmat, 2019
Background and Objectives: The Drug Package Insert (PI) is a written information provided by drug manufacturers to deliver essential information for the consumer.
Sedigheh Mirzadeh Qasabeh, Vahideh Zareh Gavgani   +1 more
doaj  

Findings on In Vitro Transporter-Mediated Drug Interactions and Their Follow-Up Actions for Labeling: Analysis of Drugs Approved by US FDA between 2017 and 2021

Pharmaceutics, 2022
Understanding possible follow-up actions on in vitro findings helps determine the necessity of labeling for drug interactions. We analyzed information for in vitro findings on transporter-mediated interactions of drugs approved by the U.S.
Kyeong-Ryoon Lee, Ji-Eun Chang, Jongmin Yoon, Hyojeong Jin, Yoon-Jee Chae   +4 more
doaj   +1 more source

Linking structure and function of the asialoglycoprotein receptor H1-CRD using site-directed mutagenesis and isotope labeling [PDF]

, 2007
The asialoglycoprotein receptor (ASGP-R) is a C-type lectin, abundantly expressed on hepatocytes. It mediates the clearance of desialylated glycoproteins carrying terminal galactose (Gal) or N-acetyl-galactosamine (GalNAc) residues through endocytosis ...
Johansson, Anna Karin
core   +1 more source

FDA drug labeling: rich resources to facilitate precision medicine, drug safety, and regulatory science [PDF]

, 2016
Here, we provide a concise overview of US Food and Drug Administration (FDA) drug labeling, which details drug products, drug–drug interactions, adverse drug reactions (ADRs), and more.
Harris, Stephen C., Liu, Zhichao, Rosario, Lilliam, Fang, Hong, Tong, Weida, Zhou, Guangxu, Zhang, Guoping, Xu, Joshua, Howard, Paul C.   +8 more
core   +1 more source

Current practices in organization of anesthesia drug tray

Asian Journal of Medical Sciences, 2022
Background: The risk of medication error is high in the operating room, since the anesthesiologist prepares, stores, and administers the medication. Poor labeling practices and cluttered drug trays increase the risk of syringe swap and medication error ...
Sowmya Jois , Sowmya Madihalli Janardhan Iyengar , Mahesh Chandra , Rangalakshmi Srinivasan , Arunkumar Namachivayam   +4 more
doaj   +1 more source