Results 1 to 10 of about 1,874,942 (252)

Sequential Injection Analysis for Automation and Evaluation of Drug Liberation Profiles: Clotrimazole Liberation Monitoring [PDF]

Molecules, 2021
A fully automated sequential injection system was tested in terms of its application in liberation testing, and capabilities and limitations were discussed for clotrimazole liberation from three semisolid formulations.
Hana Sklenářová, Marek Beran, Lucie Novosvětská, Daniela Šmejkalová, Petr Solich   +4 more
doaj   +5 more sources

Assessment of a mathematical model considering the effect of flow rate on in-vitro drug-release from PLGA films [PDF]

E3S Web of Conferences, 2021
Drug-eluting stents implanted in blood vessels are subject to various dynamics of blood flow. In this study, we present the evaluation of a mathematical model considering the effect of flow rate, to simulate the kinetic profiles of drug release ...
Abbasnezhad Navideh, Bakir Farid, Champmartin Stéphane, Shirinbayan Mohammadali   +3 more
doaj   +1 more source

Vitamin E Lipid-Based Nanodevices as a Tool for Ovine Sperm Protection against Oxidative Stress: Impact on Sperm Motility

Antioxidants, 2022
The advent of nanotechnology in the field of animal reproduction has led to the development of safer and more efficient therapies. The use of nanotechnology allows us to avoid the detrimental effects of certain traditional antioxidants, such as Vitamin E.
Alejandro Jurado-Campos, Pedro Javier Soria-Meneses, María Arenas-Moreira, Carlos Alonso-Moreno, Iván Bravo, Virginia Rodríguez-Robledo, Irene Sánchez-Ajofrín, Ana Josefa Soler, José Julián Garde, María del Rocío Fernández-Santos   +9 more
doaj   +1 more source

Numerical prediction of drug release from polyurethane samples combining kinetic model developed by experimental data [PDF]

E3S Web of Conferences, 2021
With the aim of optimizing Drug Eluting Stents (DES), particular attention has been laid on computational methods of controlling the drug release profile among researchers.
Song Jianfei, Abbasnezhad Navideh, Specklin Mathieu, Shirinbayan Mohammadali, Kouidri Smaine, Bakir Farid   +5 more
doaj   +1 more source

Positive associations between sex hormones, bone metabolism and cognitive impairment in Chinese oldest-old females

BMC Psychiatry, 2023
Purpose With a rapid increase in older adults, progressive impairment in cognitive function has become an increasing concern owing to high social and economic burdens.
Long Feng, Lihua Bian, Chaoxue Ning, Pei Zhang, Yali Zhao, Zhitao Gao, Ping Ping, Shihui Fu   +7 more
doaj   +1 more source

Machine learning-based models to predict one-year mortality among Chinese older patients with coronary artery disease combined with impaired glucose tolerance or diabetes mellitus

Cardiovascular Diabetology, 2023
Purpose An accurate prediction of survival prognosis is beneficial to guide clinical decision-making. This prospective study aimed to develop a model to predict one-year mortality among older patients with coronary artery disease (CAD) combined with ...
Yan Li, Lixun Guan, Chaoxue Ning, Pei Zhang, Yali Zhao, Qiong Liu, Ping Ping, Shihui Fu   +7 more
doaj   +1 more source

Associations between lipid profiles and late‐life cognitive impairment among oldest‐old and centenarian adults

MedComm, 2023
Dyslipidemia and cognitive impairment are common among old adults and the occurrence of them rises exponentially with increasing age. Evidences of the relationships between serum lipids and cognitive impairment are inconsistent or equivocal among older ...
Yujian Chen, Kaidi Yang, Ya Huang, Xuejiao Wang, Yali Zhao, Ping Ping, Shasha Guan, Shihui Fu   +7 more
doaj   +1 more source

WGCNA and molecular docking identify hub genes for cardiac aging

Frontiers in Cardiovascular Medicine, 2023
BackgroundCardiac aging and ageing-related cardiovascular diseases remain increase medical and social burden. Discovering the molecular mechanisms associated with cardiac aging is expected to provide new perspectives for delaying aging and related ...
Ping Ping, Lixun Guan, Chaoxue Ning, Qiong Liu, Yali Zhao, Xiang Zhu, Ting Yang, Shihui Fu, Shihui Fu   +8 more
doaj   +1 more source

Silver-hollow mesoporous silica nanoparticles for clarithromycin delivery in an animal model of helicobacter pylori [PDF]

Nanomedicine Journal
Background: Nanoparticle-based drug delivery systems offer a promising approach to overcoming antimicrobial resistance and enhancing therapeutic efficacy.Objective(s): This study aimed to evaluate the efficacy of silver-hollow mesoporous silica ...
Soroush Mirfakhraee, Reza Mirnejad, Maryam Iman   +2 more
doaj   +1 more source

In vitro biopharmaceutical equivalence of drugs used in the treatment of tuberculosis in Peru [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Medicines are vital for public health, and it is essential to ensure their quality. This is especially important with multisource medications, which have not undergone clinical trials and may have limited bioavailability.
Luis A. Rodríguez-Hidalgo, Pedro M. Alva-Plasencia, Luis A. Concepción-Urteaga, Julio Hilario-Vargas, Olga E. Caballero-Aquiño, Vanessa Saldaña-Bobadilla, Amalia G. Vega-Fernandez   +6 more
doaj   +1 more source