Results 21 to 30 of about 29,922 (309)

WGCNA and molecular docking identify hub genes for cardiac aging

Frontiers in Cardiovascular Medicine, 2023
BackgroundCardiac aging and ageing-related cardiovascular diseases remain increase medical and social burden. Discovering the molecular mechanisms associated with cardiac aging is expected to provide new perspectives for delaying aging and related ...
Ping Ping, Lixun Guan, Chaoxue Ning, Qiong Liu, Yali Zhao, Xiang Zhu, Ting Yang, Shihui Fu, Shihui Fu   +8 more
doaj   +1 more source

Silver-hollow mesoporous silica nanoparticles for clarithromycin delivery in an animal model of helicobacter pylori [PDF]

Nanomedicine Journal
Background: Nanoparticle-based drug delivery systems offer a promising approach to overcoming antimicrobial resistance and enhancing therapeutic efficacy.Objective(s): This study aimed to evaluate the efficacy of silver-hollow mesoporous silica ...
Soroush Mirfakhraee, Reza Mirnejad, Maryam Iman   +2 more
doaj   +1 more source

Sex hormones and physical function among the Chinese oldest-old and centenarian women

Journal of Translational Medicine, 2022
Background Physical independence is crucial for overall health in the elderly individuals. The life expectancy of women has been shown to be higher than that of men, which is also known as the “male–female health-survival paradox”.
Qiao Zhu, Ping Ping, Pei Zhang, Chaoxue Ning, Yali Zhao, Yao Yao, Xiubing Li, Shihui Fu   +7 more
doaj   +1 more source

In vitro biopharmaceutical equivalence of drugs used in the treatment of tuberculosis in Peru [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Medicines are vital for public health, and it is essential to ensure their quality. This is especially important with multisource medications, which have not undergone clinical trials and may have limited bioavailability.
Luis A. Rodríguez-Hidalgo, Pedro M. Alva-Plasencia, Luis A. Concepción-Urteaga, Julio Hilario-Vargas, Olga E. Caballero-Aquiño, Vanessa Saldaña-Bobadilla, Amalia G. Vega-Fernandez   +6 more
doaj   +1 more source

Prevalence and correlates of malnutrition risk among Chinese centenarians and oldest-old adults

iScience, 2023
Summary: This study was to explore epidemiological characteristics of malnutrition and factors associated with malnutrition in centenarians and oldest-old adults, so as to provide a reference for family members and government departments to take ...
Songmei Han, Dongxu Zhao, Ping Ping, Pei Zhang, Yali Zhao, Kaidi Yang, Xuejiao Wang, Shihui Fu   +7 more
doaj   +1 more source

On dissolution test for Hypertril tablets using high performance liquid chromatography

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2019
Particular attention is paid to the release of the active ingredients of drugs in the form of tablets. Therefore, we have developed a method for determining the dissolution test, for the original drug Hypertril. The purpose.
L. I. Kucherenko, N. V. Parniuk, Z. B. Moriak, L. H. Cherkovska, H. I. Tkachenko   +4 more
doaj   +1 more source

Potential use of the S-protein–Angiotensin converting enzyme 2 binding pathway in the treatment of coronavirus disease 2019

Frontiers in Public Health, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen that causes coronavirus disease 2019 (COVID-19), infects humans through a strong interaction between the viral spike protein (S-protein) and angiotensin converting enzyme 2 (ACE2)
Long Feng, Shihui Fu, Shihui Fu, Pei Zhang, Yujie Zhang, Yali Zhao, Yao Yao, Leiming Luo, Ping Ping   +8 more
doaj   +1 more source

Sutures modified by incorporation of chlorhexidine and cinnamaldehyde: anti-Candida effect, bioavailability and mechanical properties

Revista de Odontologia da UNESP, 2019
Introduction Antimicrobial sutures are a therapeutic alternative for the control of oral infections. Objective Incorporate Chlorhexidine (CHX) and Cinnamaldehyde (CN) in sutures and evaluate the anti-Candida effect, release of antimicrobials and ...
Raphael Cavalcante COSTA, Yuri Wanderley CAVALCANTI, Ana Maria Gondim VALENÇA, Leopoldina de Fátima Dantas de ALMEIDA   +3 more
doaj   +1 more source

Towards functional characterization of excipients for oral solid dosage forms using UV-vis imaging. Liberation, release and dissolution

, 2021
The purpose of this study was to investigate whole-dosage form UV-vis imaging as a potential tool for functional characterization of excipients used in solid oral dosage forms.
Sun, Yu, Bar-Shalom, Daniel, Mu, Huiling, Ostergaard, Jesper, Larsen, Susan Weng, Li, Zhuoxuan, Jensen, Henrik   +6 more
core   +1 more source

Relationships Between Traditional Chinese Medicine Constitution and Age-Related Cognitive Decline in Chinese Centenarians

Frontiers in Aging Neuroscience, 2022
BackgroundAge-related cognitive decline (ARCD) is a common condition among older adults, affecting 100 million people worldwide. Traditional Chinese Medicine’s (TCM) constitution is closely related to the occurrence and development of diseases in the ...
Zhigao Sun, Ping Ping, Yulong Li, Long Feng, Fan Liu, Yali Zhao, Yao Yao, Yao Yao, Pei Zhang, Shihui Fu, Shihui Fu   +10 more
doaj   +1 more source