Results 51 to 60 of about 12,013,030 (353)

Safety and Efficacy of Anticoagulation Therapy in Paediatric Patients With Solid Tumours or Lymphomas at Risk of Thrombocytopenia: A Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Patients with solid tumours or lymphomas have an increased risk of thromboembolism (TE) and thrombocytopenia. Evidence‐based strategies for anticoagulation therapy (ACT) for patients with thrombocytopenia are limited. We examined the impact of thrombocytopenia on ACT administration and bleeding incidence in children with solid ...
Andrés Felipe Fajardo   +5 more
wiley   +1 more source

Off-label use catalogue of tumor anti-angiogenic drugs in China: a narrative review

open access: yesFrontiers in Pharmacology
BackgroundThe management of off-label use (OLU) is an important aspect of standardizing and promoting the rational use of antitumor drugs. Tumor anti-angiogenic therapy (AAT) is essential in cancer treatment.
Difei Yao   +13 more
doaj   +1 more source

Antioxidant properties of drugs used in Type 2 diabetes management: could they contribute to, confound or conceal effects of antioxidant therapy?

open access: yesRedox Report, 2018
Objectives: This is a narrative review, investigating the antioxidant properties of drugs used in the management of diabetes, and discusses whether these antioxidant effects contribute to, confound, or conceal the effects of antioxidant therapy. Methods:
Siu Wai Choi, Cyrus K. Ho
doaj   +1 more source

Drug management of oxidation-reduction state of the body in respiratory tract diseases (part 6)

open access: yesZdorovʹe Rebenka, 2018
The review of the literature presents mo­dern data on antioxidant and anti-inflammatory acti­vity of polyphenols, as well as their representatives curcumin and resveratrol in diseases of the respiratory system.
A.E. Abaturov   +2 more
doaj   +1 more source

Survival for Children Diagnosed With Wilms Tumour (2012–2022) Registered in the UK and Ireland Improving Population Outcomes for Renal Tumours of Childhood (IMPORT) Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Improving Population Outcomes for Renal Tumours of childhood (IMPORT) is a prospective clinical observational study capturing detailed demographic and outcome data on children and young people diagnosed with renal tumours in the United Kingdom and the Republic of Ireland.
Naomi Ssenyonga   +56 more
wiley   +1 more source

Analysis of Medication Inventory System for Intensive Care Unit: A Hospital Example

open access: yesTürk Yoğun Bakim Derneği Dergisi
Objective: Optimizing health benefits becomes essential given the limitations of universal healthcare resources. Therefore, this study aims to conduct an always, better, and control (ABC) and vital, essential, and desirable (VED) analysis of medications ...
Alkan Durmuş   +2 more
doaj   +1 more source

Preoperative Cytopenia in Patients Affected by High‐Risk Neuroblastoma: Just a Matter of Platelets?

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims In patients affected by high‐risk neuroblastoma (HR‐NB), complete macroscopic resection (CMR) is associated with better outcomes. These patients are often cytopenic due to intensive induction regimens. The aim of the present study is to assess the impact of preoperative cytopenia on surgical outcome in patients with HR‐NB ...
Giorgio Persano   +13 more
wiley   +1 more source

What to Do When Medical Evidence Can Only Be Generated Through Routine Data: An Example From Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt   +2 more
wiley   +1 more source

Contemporary management of drug-packers [PDF]

open access: yesWorld Journal of Emergency Surgery, 2007
Experience with management of drug-packers (mules) is variable among different centres. However, despite a recorded increase in drug trafficking in general, as yet, no unified, clear guidelines exist to guide the medical management of those who only occasionally encounter these individuals.
Cahill RA   +3 more
openaire   +3 more sources

Management of Chronic Heart Failure in Dialysis Patients: A Challenging but Rewarding Path

open access: yesReviews in Cardiovascular Medicine
Chronic heart failure (CHF) is a common complication and cause of death in dialysis patients. Although several clinical guidelines and expert consensus on heart failure (HF) in the general population have been issued in China and abroad, due to abnormal ...
Luxuan Guo   +10 more
doaj   +1 more source

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