Results 41 to 50 of about 1,207,344 (315)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Off-label use catalogue of tumor anti-angiogenic drugs in China: a narrative review

Frontiers in Pharmacology
BackgroundThe management of off-label use (OLU) is an important aspect of standardizing and promoting the rational use of antitumor drugs. Tumor anti-angiogenic therapy (AAT) is essential in cancer treatment.
Difei Yao, Difei Yao, Yangmin Hu, Yangmin Hu, Shanshan Weng, Tiantian Wang, Tao Zhu, Tao Zhu, Lulu Liu, Huan Luo, Wei He, Wei He, Haibin Dai, Haibin Dai   +13 more
doaj   +1 more source

Antioxidant properties of drugs used in Type 2 diabetes management: could they contribute to, confound or conceal effects of antioxidant therapy?

Redox Report, 2018
Objectives: This is a narrative review, investigating the antioxidant properties of drugs used in the management of diabetes, and discusses whether these antioxidant effects contribute to, confound, or conceal the effects of antioxidant therapy. Methods:
Siu Wai Choi, Cyrus K. Ho
doaj   +1 more source

Drug management of oxidation-reduction state of the body in respiratory tract diseases (part 6)

Zdorovʹe Rebenka, 2018
The review of the literature presents mo­dern data on antioxidant and anti-inflammatory acti­vity of polyphenols, as well as their representatives curcumin and resveratrol in diseases of the respiratory system.
A.E. Abaturov, A.P. Volosovets, T.P. Borysova   +2 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Drug Enforcement Program, fiscal year 2002/2003, State of Connecticut [PDF]

, 2002
Electronic data.; Title from PDF cover (viewed Aug. 10, 2006).; "Application Due Date: Friday, March 22, 2002, 4:30 p.m., at the Office of Policy and Management.
Drug Enforcement Program (Conn.)
core  

Patterns of anti-malarial drug treatment among pregnant women in Uganda. [PDF]

, 2011
BACKGROUND: Prompt use of an effective anti-malarial drug is essential for controlling malaria and its adverse effects in pregnancy. The World Health Organization recommends an artemisinin-based combination therapy as the first-line treatment of ...
Staedke Sarah G, Sarah G Staedke, Brentlinger Paula E, Andy Stergachis, Paula E Brentlinger, Stergachis, Andy, Laura R Sangaré, Richardson, Barbra A, Staedke, Sarah G, Weiss Noel S, Barbra A Richardson, Weiss, Noel S, Stergachis Andy, Mpungu S Kiwuwa, Kiwuwa, Mpungu S, Sangaré Laura R, Brentlinger, Paula E, Kiwuwa Mpungu S, Richardson Barbra A, Noel S Weiss, Sangaré, Laura R   +20 more
core   +1 more source

An Overview of Herbal-Based Antidiabetic Drug Delivery Systems: Focus on Lipid- and Inorganic-Based Nanoformulations [PDF]

, 2022
Diabetes is a metabolic pathology with chronic high blood glucose levels that occurs when the pancreas does not produce enough insulin or the body does not properly use the insulin it produces.
Beloqui Garcia, Ana, Beloqui, Ana, Joëlle Quetin-Leclercq, Espoir K. Kambale, Kambale, Espoir K., Memvanga, Patrick B., Quetin-Leclercq, Joëlle, Ana Beloqui, Kambale Kavungere, Espoir, Patrick B. Memvanga, Memvanga, Patrick B   +10 more
core   +1 more source

Analysis of Medication Inventory System for Intensive Care Unit: A Hospital Example

Türk Yoğun Bakim Derneği Dergisi
Objective: Optimizing health benefits becomes essential given the limitations of universal healthcare resources. Therefore, this study aims to conduct an always, better, and control (ABC) and vital, essential, and desirable (VED) analysis of medications ...
Alkan Durmuş, Özlem Öner, Ali Necati Gökmen   +2 more
doaj   +1 more source

Clinical outcomes and treatment patterns of older adults with dementia-related psychosis by dementia type in the United States

BMC Geriatrics, 2022
Background Little is known about the incidence of clinical events and treatment patterns among older adults with dementia-related psychosis. Given that dementia-related psychosis comprises various dementia types, this study describes the incidence of ...
Joan Forns, Heather E. Danysh, Lisa J. McQuay, Mary Ellen Turner, Colleen Dempsey, Mary S. Anthony, George Demos, J. Bradley Layton   +7 more
doaj   +1 more source